(2S,4S)-(−)-4-Diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine
(2S,4S)-(−)-4-Diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine (CAS: 61478-29-3) is a chiral phosphine ligand with the molecular formula C29H29NP2 and a molecular weight of 453.49 g/mol. This compound is primarily utilized in asymmetric synthesis and as a chiral catalyst, facilitating stereoselective chemical transformations. Its structure makes it valuable for developing enantiomerically pure compounds in various chemical research and development settings.
- IUPAC
- PPM
- Synonyms
- C29H29NP2

Chiral Ligand in Asymmetric Catalysis
This pyrrolidine-based phosphine ligand is employed to create chiral metal complexes that catalyse asymmetric reactions, leading to the formation of enantiomerically enriched products.
Stereoselective Synthesis
It serves as a key component in synthesising chiral molecules, enabling control over stereochemistry in reactions crucial for pharmaceutical and fine chemical development.
Research and Development
Utilised in academic and industrial laboratories for exploring novel catalytic systems and developing new synthetic methodologies requiring chiral induction.
| Molecular weight | 453.49 |
|---|---|
| Empirical formula | C29H29NP2 |
| Assay | ≥98.0% (CHN) |
| Optical activity | [α]20/D −15.5±1°, c = 1% in benzene |
| Melting point | 102-104 °C(lit.)102-104 °C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,4S)-(−)-4-Diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine used for?
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(2S,4S)-(−)-4-Diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine is primarily used as a chiral ligand in asymmetric synthesis and catalysis, facilitating the stereoselective formation of chiral molecules.
What is the CAS number and molecular formula for this compound?
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The CAS number is 61478-29-3, and the molecular formula is C29H29NP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a purity of ≥98.0% (CHN). TSS does not represent this product as USP, BP, or EP grade.
How should (2S,4S)-(−)-4-Diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine be handled safely?
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Handling requires a dust mask type N95 (US), eyeshields, and gloves. It is classified as Warning, with hazards including H302, H312, and H332 (Harmful if swallowed, in contact with skin, or if inhaled). Ensure adequate ventilation and avoid dust formation.
Is this product available for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product.
How can I request a sample or quote?
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Please contact our sales team via the website or provide your details through the 'Request a Quote' or 'Request a Sample' functions.
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