(2S,4S)-(+)-Pentanediol
(2S,4S)-(+)-Pentanediol (CAS: 72345-23-4) is a chiral polyol with the molecular formula C5H12O2 and a molecular weight of 104.15 g/mol. This optically active compound serves as a valuable building block in asymmetric synthesis. It is particularly noted for its use in the preparation of NIP-101, a potent calcium antagonist, highlighting its significance in pharmaceutical research and development.
- IUPAC
- (S,S)-(+)-2,4-Pentanediol,[S-(S*,S*)]-(+)-2,4-Pentanediol
- Synonyms
- (S,S)-(+)-2,4-Pentanediol[S-(S*,S*)]-(+)-2,4-Pentanediol
Chiral Building Block in Asymmetric Synthesis
(2S,4S)-(+)-Pentanediol is an optically active reagent utilised in asymmetric synthesis. Its defined stereochemistry makes it a crucial component for creating complex chiral molecules with specific spatial arrangements.
Precursor for Pharmaceutical Intermediates
This compound is specifically employed in the synthesis of NIP-101, a potent calcium antagonist. This application underscores its importance in the development of pharmacologically active agents.
Organic Synthesis Reagent
As a versatile diol, (2S,4S)-(+)-Pentanediol can participate in various organic transformations. It serves as a useful starting material or intermediate in the synthesis of more complex organic structures.
| Molecular weight | 104.15 |
|---|---|
| Linear formula | CH3CH(OH)CH2CH(OH)CH3 |
| Assay | 99% |
| Optical activity | [α]20/D +39.8°, c = 10 in chloroform |
| Application | Optically active reagent used to prepare NIP-101, a potent calcium antagonist.1 |
| Melting point | 45-48 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,4S)-(+)-Pentanediol primarily used for?
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(2S,4S)-(+)-Pentanediol is an optically active reagent used to prepare NIP-101, a potent calcium antagonist, and serves as a chiral building block in asymmetric synthesis.
What is the CAS number and chemical formula for (2S,4S)-(+)-Pentanediol?
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The CAS number for (2S,4S)-(+)-Pentanediol is 72345-23-4, and its linear formula is CH3CH(OH)CH2CH(OH)CH3.
What grade and purity does Tech Serve Solutions supply for (2S,4S)-(+)-Pentanediol?
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Tech Serve Solutions supplies (2S,4S)-(+)-Pentanediol with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should (2S,4S)-(+)-Pentanediol be handled safely?
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Handle (2S,4S)-(+)-Pentanediol with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The flash point is 101 °C (213.8 °F), indicating it is combustible.
Is (2S,4S)-(+)-Pentanediol exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (2S,4S)-(+)-Pentanediol.
How can I request a quote or sample for (2S,4S)-(+)-Pentanediol?
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Please contact our sales team via the website or phone to request a quote or sample for (2S,4S)-(+)-Pentanediol.
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