(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane

CAS 98737-29-2C15H21NO3Chemical Synthesis

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane (CAS: 98737-29-2) is a chiral epoxide with the molecular formula C15H21NO3 and a molecular weight of 263.33 g/mol. This compound serves as a critical building block in asymmetric synthesis. Its primary application lies in the development and manufacturing of HIV-1 protease inhibitors, contributing to the synthesis of vital pharmaceutical agents.

IUPAC: tert-Butyl [S-(R*,R*)]-(−)-(1-oxiranyl-2-phenylethyl)carbamate
Synonyms: 98737-29-2C15H21NO3tert-Butyl [S-(R*,R*)]-(−)-(1-oxiranyl-2-phenylethyl)carbamate

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(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane (C15H21NO3) — chemical structure, CAS 98737-29-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Application IndexAsymmetric SynthesisBiochemicals and ReagentsCell Signaling EnzymesChemical SynthesisChiral Building BlocksEnzymesInhibitorsand SubstratesEpoxides

01 /Applications

Synthesis of HIV Protease Inhibitors

This compound is a key intermediate in the synthesis of HIV-1 protease inhibitors. Its chiral epoxide structure is crucial for building the complex molecular architectures required for these therapeutic agents.

Asymmetric Synthesis

Utilised as a chiral building block in asymmetric synthesis, enabling the stereoselective creation of complex organic molecules. Its specific stereochemistry is vital for applications requiring high enantiomeric purity.

Organic Building Block

A versatile organic building block employed in various chemical synthesis pathways. It is particularly valuable for introducing specific functional groups and stereocentres into target molecules.

02 /Properties

Molecular weight	263.33
Empirical formula	C15H21NO3
Assay	99%
Optical activity	[α]23/D −7°, c = 0.6 in methanol
Application	Building block employed in the synthesis of HIV-1 protease inhibitors.1,2
Melting point	125-127 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Environmental hazard (GHS09) — Environmental hazard

Warning

Hazard statements

H410Very toxic to aquatic life with long-lasting effects

Precautionary statements

P273Avoid release to the environment
P501Dispose of contents and container per local regulations

Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	N
Risk statements (R)	50/53
Safety statements (S)	60-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

98737-29-2

MDL number

MFCD02258997

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane primarily used for?

This compound is primarily used as a building block in the synthesis of HIV-1 protease inhibitors and in general asymmetric synthesis due to its chiral epoxide structure.

What is the CAS number and chemical formula for this product?

The CAS number is 98737-29-2 and the empirical formula is C15H21NO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 99%. It is supplied as a research or technical grade material and is not intended for pharmaceutical, food, or any other regulated application unless explicitly stated otherwise.

What are the main safety concerns when handling this chemical?

This chemical is classified under GHS09 with the signal word 'Warning' and carries the hazard statement H410 (Very toxic to aquatic life with long-lasting effects). It should be handled with appropriate precautions to prevent environmental release and exposure. Ensure proper personal protective equipment is used and it is not released into waterways.

How is (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane packed and shipped?

This product is shipped as UN 3077, Class 9, Packing Group III. Detailed packing and shipping information for export can be provided upon request.

How can I request a sample or a quote for this chemical?

To request a sample or a quote, please use the contact form on our website or contact our sales department directly. Please include the product name and CAS number in your request.