3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution
3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution (CAS: 112981-69-8) is an organometallic compound with a molecular weight of 306.31 g/mol. Supplied as a 0.5 M solution in THF, this Grignard reagent is characterised by the presence of two trifluoromethyl groups on the phenyl ring. It is primarily utilised in organic synthesis for the introduction of the 3,5-bis(trifluoromethyl)phenyl moiety into various molecular structures.
- Synonyms
- C7H4BrF6Mg
Organic Synthesis Reagent
Acts as a key building block for introducing the 3,5-bis(trifluoromethyl)phenyl group in complex organic molecules. Its reactivity is typical of Grignard reagents, enabling nucleophilic addition reactions.
Pharmaceutical Intermediate Synthesis
Valuable in the synthesis of novel pharmaceutical candidates, where the electron-withdrawing trifluoromethyl groups can influence pharmacokinetic properties or binding affinities.
Materials Science
Can be employed in the development of new materials, potentially influencing properties such as thermal stability or electronic characteristics due to the fluorinated aromatic system.
| Molecular weight | 306.31 |
|---|---|
| Empirical formula | C7H4BrF6Mg |
| Density | 1.015 g/mL at 25 °C(lit.) |
| Concentration | 0.5 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -20 °C / -4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution used for?
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This compound is primarily used as a reagent in organic synthesis for introducing the 3,5-bis(trifluoromethyl)phenyl group into target molecules, particularly in the development of pharmaceuticals and advanced materials.
What is the CAS number and formula for 3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution?
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The CAS number is 112981-69-8, and the empirical formula (Hill notation) is C7H4BrF6Mg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a 0.5 M solution in Tetrahydrofuran (THF). This is a technical or research grade product, and we do not represent it as USP, BP, or EP grade.
What are the main safety hazards associated with this chemical?
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This product is highly flammable (flash point -20 °C), corrosive, and can cause severe skin burns and eye damage. It may form explosive peroxides and reacts violently with water. Inhalation may cause respiratory irritation. It is also suspected of causing cancer. Handle with extreme caution in a well-ventilated area, avoiding heat, sparks, and open flames.
How is this chemical packed, shipped, and exported?
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This reagent is typically packed in appropriate containers for hazardous materials, adhering to UN 2924 shipping regulations (Class 8, Packing Group II). TSS is experienced in global exporting of such chemicals.
How can I request a sample or quote for 3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution?
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Please contact our sales team directly through the website or by phone to request a sample or a formal quotation. We are happy to assist with your specific requirements.
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