3,5-Di-tert-butyl-2-hydroxybenzaldehyde
3,5-Di-tert-butyl-2-hydroxybenzaldehyde (CAS 37942-07-7) is a valuable organic compound with the linear formula HOC<sub>6</sub>H<sub>2</sub>[C(CH<sub>3</sub>)<sub>3</sub>]<sub>2</sub>CHO and a molecular weight of 234.33 g/mol. As a substituted salicylaldehyde, it functions as a key building block in complex organic synthesis, particularly in the preparation of specialised ligands and coordination complexes.
- IUPAC
- 3,5-Di-tert-butylsalicylaldehyde
- Synonyms
- HOC6H2[C(CH3)3]2CHO3,5-Di-tert-butylsalicylaldehyde
![3,5-Di-tert-butyl-2-hydroxybenzaldehyde (HOC6H2[C(CH3)3]2CHO) — chemical structure, CAS 37942-07-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F37942-07-7.png&w=3840&q=75)
Synthesis of Schiff Base Ligands
This compound is employed in the synthesis of chiral Schiff base ligands, which are crucial for enantioselective catalysis in various chemical transformations, including copper-catalyzed additions.
Preparation of Metal Complexes
It serves as a precursor for various metal complexes, such as Mn(III)-salen complexes and tin Schiff base complexes, relevant in catalytic and coordination chemistry studies.
Development of Chiral Ligands for Organozinc Reactions
3,5-Di-tert-butyl-2-hydroxybenzaldehyde is used in the development of chiral oxazolidine ligands for the enantioselective addition of diethylzinc to aldehydes, enabling asymmetric synthesis.
| Molecular weight | 234.33 |
|---|---|
| Linear formula | HOC6H2[C(CH3)3]2CHO |
| Assay | 99% |
| Application | 3,5-Di-tert-butyl-2-hydroxybenzaldehyde was used in the synthesis of• Mn(III)-salen complex and its diamino precursor 5,6-diamino-5,6-dideoxy-1,2-O-isopropylidene-3-O-methyl-β-L-idofuranose1• chiral Schiff base ligand for an enantioselective copper-catalyzed addition of phenylacetylene to imines2• chiral oxazolidine ligand for the enantioselective addition of diethylzinc to aldehydes3• tin Schiff base complexes with histidine analogues4 |
| Melting point | 59-61 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Di-tert-butyl-2-hydroxybenzaldehyde used for?
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3,5-Di-tert-butyl-2-hydroxybenzaldehyde is used as a building block in organic synthesis, particularly for the preparation of chiral Schiff base ligands, metal complexes, and in enantioselective catalytic reactions.
What are the CAS number and formula for 3,5-Di-tert-butyl-2-hydroxybenzaldehyde?
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The CAS number is 37942-07-7 and the linear formula is HOC<sub>6</sub>H<sub>2</sub>[C(CH<sub>3</sub>)<sub>3</sub>]<sub>2</sub>CHO.
What grade and purity does Tech Serve Solutions supply for 3,5-Di-tert-butyl-2-hydroxybenzaldehyde?
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Tech Serve Solutions supplies 3,5-Di-tert-butyl-2-hydroxybenzaldehyde with an assay of 99%. It is supplied for research and development or industrial use; TSS does not represent it as USP, BP, EP, or pharmaceutical grade.
How should 3,5-Di-tert-butyl-2-hydroxybenzaldehyde be handled safely?
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3,5-Di-tert-butyl-2-hydroxybenzaldehyde is a Warning substance (GHS07) with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, in a well-ventilated area.
How is 3,5-Di-tert-butyl-2-hydroxybenzaldehyde packed and exported?
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3,5-Di-tert-butyl-2-hydroxybenzaldehyde is carefully packed according to industry standards for safe transport and export by Tech Serve Solutions, a global supplier.
How can I request a sample or quote for 3,5-Di-tert-butyl-2-hydroxybenzaldehyde?
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To request a sample or quote for 3,5-Di-tert-butyl-2-hydroxybenzaldehyde, please contact the Tech Serve Solutions sales team via our website or direct inquiry.
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