3,5-Bis(trifluoromethyl)pyridine
3,5-Bis(trifluoromethyl)pyridine (CAS: 20857-47-0, C7H3F6N) is a fluorinated pyridine derivative with a molecular weight of 215.10 g/mol. Its structure features two trifluoromethyl groups, imparting unique electronic and steric properties. This compound serves as a valuable building block in organic synthesis, particularly for the development of novel pharmaceuticals, agrochemicals, and advanced materials where fluorination is desired.
- Synonyms
- C7H3F6N

Pharmaceutical Intermediate
Utilised in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates. Its trifluoromethyl groups can enhance metabolic stability and lipophilicity of target molecules.
Agrochemical Development
Serves as a key intermediate in the creation of novel pesticides, herbicides, and fungicides. The fluorine atoms can influence biological activity and environmental persistence.
Materials Science
Incorporated into the design of advanced materials, such as liquid crystals or polymers. The electron-withdrawing trifluoromethyl groups can modify material properties.
Research and Development
A versatile reagent for academic and industrial research, enabling the exploration of new fluorinated compounds and reaction pathways.
| Molecular weight | 215.10 |
|---|---|
| Empirical formula | C7H3F6N |
| Assay | 95% |
| Melting point | 34-38 °C |



Hazard statements
- H228Flammable solid
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 44 °C / 111.2 °F |
| Transport (UN / ADR) | UN 2926 4.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-25-37/38-41 |
| Safety statements (S) | 26-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Bis(trifluoromethyl)pyridine used for?
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3,5-Bis(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis for pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and formula for 3,5-Bis(trifluoromethyl)pyridine?
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The CAS number is 20857-47-0, and the empirical formula is C7H3F6N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Bis(trifluoromethyl)pyridine with an assay of 95%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 3,5-Bis(trifluoromethyl)pyridine be handled safely?
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This compound is classified as Danger, flammable solid, toxic if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation (H228-H301-H315-H318-H335). Handle with appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, keeping away from heat and ignition sources.
Is 3,5-Bis(trifluoromethyl)pyridine a controlled substance?
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The provided data does not indicate that 3,5-Bis(trifluoromethyl)pyridine is a controlled substance.
How is 3,5-Bis(trifluoromethyl)pyridine packed and exported?
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3,5-Bis(trifluoromethyl)pyridine is packed and exported according to international shipping regulations for hazardous materials, including UN 2926 (Flammable solid, toxic, organic, n.o.s.).
How can I request a sample or quote for 3,5-Bis(trifluoromethyl)pyridine?
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To request a sample or quote, please contact our sales team via the website or direct inquiry, providing your contact details and the quantity required.
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