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3,5-Bis(trifluoromethyl)pyridine

CAS 20857-47-0C7H3F6NChemical Synthesis

3,5-Bis(trifluoromethyl)pyridine (CAS: 20857-47-0, C7H3F6N) is a fluorinated pyridine derivative with a molecular weight of 215.10 g/mol. Its structure features two trifluoromethyl groups, imparting unique electronic and steric properties. This compound serves as a valuable building block in organic synthesis, particularly for the development of novel pharmaceuticals, agrochemicals, and advanced materials where fluorination is desired.

Synonyms
C7H3F6N
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3,5-Bis(trifluoromethyl)pyridine (C7H3F6N) — chemical structure, CAS 20857-47-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisHeterocyclic Building BlocksPyridines
01 /Applications

Pharmaceutical Intermediate

Utilised in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates. Its trifluoromethyl groups can enhance metabolic stability and lipophilicity of target molecules.

Agrochemical Development

Serves as a key intermediate in the creation of novel pesticides, herbicides, and fungicides. The fluorine atoms can influence biological activity and environmental persistence.

Materials Science

Incorporated into the design of advanced materials, such as liquid crystals or polymers. The electron-withdrawing trifluoromethyl groups can modify material properties.

Research and Development

A versatile reagent for academic and industrial research, enabling the exploration of new fluorinated compounds and reaction pathways.

02 /Properties
Molecular weight215.10
Empirical formulaC7H3F6N
Assay95%
Melting point34-38 °C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H228Flammable solid
  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point44 °C / 111.2 °F
Transport (UN / ADR)UN 2926 4.1/PG 3
Water hazard class (WGK, DE)3
Hazard codes (EU)F,T
Risk statements (R)11-25-37/38-41
Safety statements (S)26-39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
20857-47-0
MDL number
MFCD00128904
PubChem substance
24884753
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,5-Bis(trifluoromethyl)pyridine used for?

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3,5-Bis(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis for pharmaceuticals, agrochemicals, and advanced materials.

What is the CAS number and formula for 3,5-Bis(trifluoromethyl)pyridine?

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The CAS number is 20857-47-0, and the empirical formula is C7H3F6N.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3,5-Bis(trifluoromethyl)pyridine with an assay of 95%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.

How should 3,5-Bis(trifluoromethyl)pyridine be handled safely?

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This compound is classified as Danger, flammable solid, toxic if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation (H228-H301-H315-H318-H335). Handle with appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, keeping away from heat and ignition sources.

Is 3,5-Bis(trifluoromethyl)pyridine a controlled substance?

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The provided data does not indicate that 3,5-Bis(trifluoromethyl)pyridine is a controlled substance.

How is 3,5-Bis(trifluoromethyl)pyridine packed and exported?

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3,5-Bis(trifluoromethyl)pyridine is packed and exported according to international shipping regulations for hazardous materials, including UN 2926 (Flammable solid, toxic, organic, n.o.s.).

How can I request a sample or quote for 3,5-Bis(trifluoromethyl)pyridine?

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To request a sample or quote, please contact our sales team via the website or direct inquiry, providing your contact details and the quantity required.

Need 3,5-Bis(trifluoromethyl)pyridine in a specific grade or volume?