Chloromethyl phenyl sulfide
Chloromethyl phenyl sulfide (CAS: 7205-91-6; C6H5SCH2Cl; MW: 158.65) is a sulfur-containing organic compound. This reagent is primarily utilised for the thiomethylation of O-silylated lactone and ester enolates, facilitating the synthesis of alpha-methylene lactones and esters. Available from Tech Serve Solutions with an assay of 97%, it is supplied for research and chemical synthesis applications.
- IUPAC
- (Phenylthio)methyl chloride

Thiomethylation Reagent
Chloromethyl phenyl sulfide serves as a key reagent for the high-yield thiomethylation of O-silylated lactone and ester enolates. This reaction is crucial in the synthesis of valuable alpha-methylene lactones and esters.
Organic Synthesis Building Block
As an organic building block, this compound enables the introduction of the phenylthiomethyl group into various molecular structures. Its reactivity makes it useful in multi-step synthetic pathways.
Sulfur Chemistry
It is employed in studies and applications involving sulfur compounds, contributing to the development of new sulfur-containing molecules with potential applications in materials science and medicinal chemistry.
| Molecular weight | 158.65 |
|---|---|
| Linear formula | C6H5SCH2Cl |
| Assay | 97% |
| Boiling point | 66 °C/0.2 mmHg(lit.) |
| Density | 1.184 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.594(lit.) |
| Storage temperature | 2-8°C |
| Application | Reagent for the high-yield thiomethylation of O-silylated lactone and ester enolates in the synthesis of α-methylene lactones and esters.1 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloromethyl phenyl sulfide used for?
+
Chloromethyl phenyl sulfide is used as a reagent for the high-yield thiomethylation of O-silylated lactone and ester enolates in the synthesis of alpha-methylene lactones and esters.
What are the CAS number and chemical formula for Chloromethyl phenyl sulfide?
+
The CAS number for Chloromethyl phenyl sulfide is 7205-91-6, and its chemical formula is C6H5SCH2Cl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Chloromethyl phenyl sulfide with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Chloromethyl phenyl sulfide?
+
Chloromethyl phenyl sulfide is a combustible solid. Handle with appropriate personal protective equipment including eyeshields, gloves, and respiratory protection (half-mask respirator or multi-purpose combination cartridge). Store at 2-8°C.
How is Chloromethyl phenyl sulfide packed, shipped, and exported?
+
As a global supplier and exporter of fine chemicals, Tech Serve Solutions adheres to all relevant regulations for packing, shipping, and exporting Chloromethyl phenyl sulfide to meet international standards.
How can I request a sample or quote for Chloromethyl phenyl sulfide?
+
To request a sample or obtain a quote for Chloromethyl phenyl sulfide, please contact our sales team through the website or by phone.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis