Chloromethyl methyl ether
Chloromethyl methyl ether (CAS 107-30-2), with the linear formula ClCH2OCH3 and a molecular weight of 80.51 g/mol, is a vital reagent in organic synthesis. It is commonly employed for the introduction of the methoxymethyl (MOM) protecting group onto alcohols and other nucleophiles. This reagent is also utilised in preparing specific organometallic complexes, demonstrating its utility in coordination chemistry and materials science.
- IUPAC
- MOM chloride,Methoxymethyl chloride,Methyl chloromethyl ether
- Synonyms
- MOM chlorideMethoxymethyl chlorideMethyl chloromethyl ether
Methoxymethyl (MOM) Protecting Group Introduction
Chloromethyl methyl ether is widely used to install the acid-labile methoxymethyl (MOM) ether protecting group onto alcohols. This is crucial in multi-step organic syntheses where selective protection of hydroxyl groups is required.
Preparation of Organometallic Complexes
This compound serves as a precursor for preparing methoxymethyl complexes. For instance, it has been used in the synthesis of methoxymethyl complexes of manganese and rhenium, coordinated to carbonyl and dipyridyl ligands.
Organic Synthesis Reagent
As a versatile synthetic reagent, Chloromethyl methyl ether facilitates various transformations in organic chemistry, contributing to the construction of complex molecular architectures.
| Molecular weight | 80.51 |
|---|---|
| Linear formula | ClCH2OCH3 |
| Boiling point | 55-57 °C(lit.) |
| Density | 1.06 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.396(lit.) |
| Vapour pressure | 3.55 psi (20 °C) |
| Storage temperature | 2-8°C |
| Application | Used to prepare methoxymethyl complexes of Mn and Re coordinated to carbonyl and dipyridyl ligands.1 |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H319Causes serious eye irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 16 °C / 60.8 °F |
| Transport (UN / ADR) | UN 1239 3(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 45-11-20/21/22 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloromethyl methyl ether used for?
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Chloromethyl methyl ether is primarily used as a reagent for introducing the methoxymethyl (MOM) protecting group in organic synthesis and for preparing methoxymethyl complexes of transition metals.
What is the CAS number and formula for Chloromethyl methyl ether?
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The CAS number for Chloromethyl methyl ether is 107-30-2, and its linear formula is ClCH2OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloromethyl methyl ether as a reagent for research and chemical synthesis purposes. The specific purity or grade is available upon request; we do not represent this product as USP, BP, or EP grade.
How should Chloromethyl methyl ether be handled safely?
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Chloromethyl methyl ether is a highly flammable liquid and vapour (H225), harmful if swallowed, in contact with skin, or if inhaled (H302 + H312 + H332), causes serious eye irritation (H319), and may cause cancer (H350). Handle with extreme caution in a well-ventilated area or fume hood, wearing appropriate personal protective equipment including gloves, safety glasses, and a full-face respirator. Store in a cool, well-ventilated place away from heat and ignition sources, and keep refrigerated at 2-8°C.
Is Chloromethyl methyl ether a controlled substance?
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The provided safety data does not indicate that Chloromethyl methyl ether is a controlled substance. However, users should always comply with local regulations regarding its handling and use.
How is Chloromethyl methyl ether packed, shipped, and exported?
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Chloromethyl methyl ether is carefully packed in compliance with international regulations for hazardous materials. Shipping and export are managed by our experienced logistics team to ensure safe and timely delivery worldwide.
How can I request a sample or quote for Chloromethyl methyl ether?
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To request a sample or a quotation, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your specific requirements.
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