2,2,2-Trifluoroethyl trifluoroacetate
2,2,2-Trifluoroethyl trifluoroacetate (CAS 407-38-5), with the molecular formula CF3CO2CH2CF3 and a molar mass of 196.05 g/mol, is a highly fluorinated ester. This compound serves as a valuable building block in organic synthesis. It is particularly noted for its use in the preparation of specialised organophosphorus compounds, contributing to advancements in material science and chemical research. Its chemical properties make it a useful reagent in various synthetic routes.
- Synonyms
- 407-38-5CF3CO2CH2CF3
Preparation of Organophosphorus Compounds
2,2,2-Trifluoroethyl trifluoroacetate is employed in the synthesis of specific organophosphorus compounds, such as dimethyl (3,3,3-trifluoro-2,2-dihydroxypropyl)phosphonate. This application highlights its utility in creating complex molecules with tailored properties.
Organic Synthesis Building Block
As a fluorinated ester, it functions as a versatile building block in organic chemistry. Its structure allows for various chemical transformations, making it a key intermediate in the development of novel chemical entities and materials.
Reagent in Fluorination Chemistry
The presence of trifluoroacetate and trifluoroethyl groups suggests its potential utility in reactions involving fluorination or as a source of these moieties in complex syntheses. This role is crucial for introducing fluorine atoms into organic molecules.
| Molecular weight | 196.05 |
|---|---|
| Linear formula | CF3CO2CH2CF3 |
| Assay | 99% |
| Boiling point | 55 °C(lit.) |
| Density | 1.464 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.277(lit.) |
| Vapour pressure | 3.34 psi (20 °C) |
| Application | 2,2,2-Trifluoroethyl trifluoroacetate has been used in the preparation of dimethyl (3,3,3-trifluoro-2,2-dihydroxypropyl)phosphonate1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 0 °C / 32 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethyl trifluoroacetate used for?
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2,2,2-Trifluoroethyl trifluoroacetate is primarily used as a building block in organic synthesis, notably in the preparation of organophosphorus compounds like dimethyl (3,3,3-trifluoro-2,2-dihydroxypropyl)phosphonate.
What are the CAS number and formula for 2,2,2-Trifluoroethyl trifluoroacetate?
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The CAS number is 407-38-5 and the linear formula is CF3CO2CH2CF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethyl trifluoroacetate with an assay of 99%. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
How should 2,2,2-Trifluoroethyl trifluoroacetate be handled?
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2,2,2-Trifluoroethyl trifluoroacetate is a flammable liquid and causes severe skin burns and eye damage (H225-H314). Handle with extreme care, using appropriate personal protective equipment including faceshields, gloves, goggles, and a suitable respirator. Ensure good ventilation and keep away from ignition sources.
How is 2,2,2-Trifluoroethyl trifluoroacetate packed and shipped?
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This product is classified under UN 2924, Hazard Class 8(3), Packing Group II, indicating it is shipped as a corrosive and flammable liquid. International shipping and export are available through Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or sample of 2,2,2-Trifluoroethyl trifluoroacetate, please contact our sales team through the website or direct inquiry channels.
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