2,2,2-Trifluoroethyl methanesulfonate
2,2,2-Trifluoroethyl methanesulfonate (CAS 25236-64-0) is a chemical compound with the linear formula CH3SO3CH2CF3 and a molecular weight of 178.13. This organosulfur compound is recognised for its utility as a building block in organic synthesis and chemical research. Its properties make it a valuable reagent for introducing the trifluoroethyl group in various chemical transformations.
- Synonyms
- 25236-64-0CH3SO3CH2CF3

Organic Synthesis Reagent
Serves as a key intermediate in the synthesis of more complex organic molecules. Its structure allows for versatile reactions in the development of novel compounds.
Chemical Research and Development
Utilised in laboratory settings for exploring new reaction pathways and developing innovative chemical processes. Its specific reactivity profile is of interest to researchers.
Building Block for Fluorinated Compounds
A useful precursor for constructing molecules containing the trifluoroethyl moiety, which can impart unique properties to target compounds.
| Molecular weight | 178.13 |
|---|---|
| Linear formula | CH3SO3CH2CF3 |
| Assay | ≥98.0% (GC) |
| Density | 1.513 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.367 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethyl methanesulfonate used for?
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2,2,2-Trifluoroethyl methanesulfonate is primarily used as a building block in organic synthesis and for chemical research and development. It is valuable for introducing the trifluoroethyl group into various molecules.
What are the CAS number and formula for 2,2,2-Trifluoroethyl methanesulfonate?
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The CAS number is 25236-64-0, and the linear formula is CH3SO3CH2CF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethyl methanesulfonate with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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This compound is classified as corrosive (GHS05, Danger, H314). Appropriate personal protective equipment, including full-face respirators, gloves, and goggles, is essential. Handle with extreme care to avoid contact with skin, eyes, and clothing.
How is 2,2,2-Trifluoroethyl methanesulfonate shipped and exported?
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As a global supplier and exporter of fine chemicals, Tech Serve Solutions adheres to all relevant regulations for the safe packing, shipping, and export of 2,2,2-Trifluoroethyl methanesulfonate.
How can I request a sample or quote for 2,2,2-Trifluoroethyl methanesulfonate?
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To request a sample or a quote, please contact our sales department through the details provided on the Tech Serve Solutions website.
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