2,2,2-Trifluoroethyl p-toluenesulfonate
2,2,2-Trifluoroethyl p-toluenesulfonate (CAS 433-06-7) is an organic sulfur compound with the linear formula CH3C6H4SO3CH2CF3 and a molecular weight of 254.23 g/mol. This tosylate ester is primarily utilised as a building block in chemical synthesis. It is a valuable intermediate for introducing the trifluoroethoxy group in organic molecules, finding applications in the development of novel compounds within research and development settings.
- Synonyms
- 433-06-7CH3C6H4SO3CH2CF3
Synthesis of Organoboranes
2,2,2-Trifluoroethyl p-toluenesulfonate has been employed in the synthesis of 1-alkyl-2,2-difluorovinylboranes. This application highlights its utility in constructing specialised organoboron compounds relevant to synthetic chemistry research.
Organic Synthesis Intermediate
As a tosylate ester, this compound serves as an effective alkylating agent. Its trifluoroethyl group can be readily incorporated into various organic structures, facilitating the creation of fluorinated molecules.
Building Block for Fluorinated Compounds
The presence of the trifluoroethyl moiety makes 2,2,2-Trifluoroethyl p-toluenesulfonate a key reagent for accessing molecules with enhanced chemical stability or specific electronic properties due to fluorine substitution.
| Molecular weight | 254.23 |
|---|---|
| Linear formula | CH3C6H4SO3CH2CF3 |
| Assay | 99% |
| Boiling point | 87-92 °C/0.1 mmHg(lit.) |
| Application | 2,2,2-Trifluoroethyl p-toluenesulfonate was used in the synthesis of 1-alkyl-2,2-difluorovinylboranes1. |
| Melting point | 36-38 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethyl p-toluenesulfonate used for?
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It is used as a building block in organic synthesis, particularly for introducing the 2,2,2-trifluoroethyl group into molecules and in the synthesis of specific organoboron compounds like 1-alkyl-2,2-difluorovinylboranes.
What is the CAS number and formula for 2,2,2-Trifluoroethyl p-toluenesulfonate?
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The CAS number is 433-06-7 and the linear formula is CH3C6H4SO3CH2CF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethyl p-toluenesulfonate with an assay of 99%. This product is supplied for laboratory and research use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 2,2,2-Trifluoroethyl p-toluenesulfonate be handled?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves should be worn. Ensure good ventilation.
Is 2,2,2-Trifluoroethyl p-toluenesulfonate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,2,2-Trifluoroethyl p-toluenesulfonate.
How can I request a quote or sample?
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Please use the 'Request a Quote' or 'Request a Sample' options available on our product page, or contact our sales department directly.
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