2,2,2-Trifluoroethyl formate
2,2,2-Trifluoroethyl formate (CAS: 32042-38-9) is a versatile organic compound with the linear formula CF 3 CH 2 OC(O)H and a molecular weight of 128.05 g/mol. It is primarily utilised as a reagent for the efficient formylation of alcohols and amines. Its reactivity makes it a valuable building block in various chemical synthesis pathways, particularly in organic chemistry research and development.
- IUPAC
- TFEF
- Synonyms
- 32042-38-9CF3CH2OC(O)H
Formylation Reagent
2,2,2-Trifluoroethyl formate serves as an effective reagent for introducing a formyl group. It is particularly useful for the formylation of alcohols and amines, yielding the corresponding formates and formamides, respectively.
Organic Synthesis Building Block
As a reactive ester containing a trifluoroethyl group, this compound is a valuable building block in organic synthesis. It facilitates the construction of more complex molecules in research and development settings.
Hydroxylamine Formylation
This reagent is noted for its utility in achieving high yields of N-formylated products when reacting with hydroxylamines, as documented in chemical literature.
| Molecular weight | 128.05 |
|---|---|
| Linear formula | CF3CH2OC(O)H |
| Assay | 95% |
| Density | 1.317 g/mL at 25 °C |
| Refractive index | n20/D <1.001 |
| Application | Reagent for the formylation of alcohols and amines. Hydroxylamines provide high yields of the N-formylated product.1 |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 7 °C / 44.6 °F |
| Transport (UN / ADR) | UN 1993BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethyl formate used for?
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2,2,2-Trifluoroethyl formate is primarily used as a reagent for the formylation of alcohols and amines, and as a building block in organic synthesis.
What are the CAS number and chemical formula for 2,2,2-Trifluoroethyl formate?
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The CAS number is 32042-38-9, and the linear formula is CF 3 CH 2 OC(O)H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethyl formate with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 2,2,2-Trifluoroethyl formate be handled safely?
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2,2,2-Trifluoroethyl formate is a highly flammable liquid and vapour (H225) and is harmful if swallowed (H302) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, away from ignition sources.
Is 2,2,2-Trifluoroethyl formate suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,2,2-Trifluoroethyl formate, complying with international shipping regulations.
How can I request a sample or quote for 2,2,2-Trifluoroethyl formate?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for 2,2,2-Trifluoroethyl formate.
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