2,2,2-Trifluoroethanol
2,2,2-Trifluoroethanol (CAS: 75-89-8), with the molecular formula CF3CH2OH and a molar mass of 100.04 g/mol, is a clear, colourless liquid. This fluorinated alcohol exhibits unique solvent properties and reactivity, making it valuable in chemical synthesis. It is commonly employed as a solvent in organic reactions, a building block for fluorinated compounds, and in specialised applications requiring its distinct characteristics. Tech Serve Solutions supplies this chemical with a focus on purity for research and industrial use.
- IUPAC
- Trifluoroethyl alcohol
- Synonyms
- 75-89-8CF3CH2OHTrifluoroethyl alcohol
Specialty Solvent
2,2,2-Trifluoroethanol serves as a highly effective polar solvent for various organic reactions, particularly those involving peptides and proteins due to its ability to disrupt hydrogen bonding. Its high ionizing power is beneficial for certain reaction mechanisms.
Chemical Synthesis Intermediate
It functions as a key building block in the synthesis of fluorinated organic compounds, including pharmaceuticals and agrochemicals. The trifluoromethyl group imparts unique properties to the target molecules.
Polymer Chemistry
This compound can be used as a solvent or co-solvent in the processing and synthesis of certain polymers, where its solvency characteristics are advantageous for specific polymer systems.
Analytical Reagent
In analytical chemistry, 2,2,2-Trifluoroethanol may be used in specific assay methods or as a mobile phase component in chromatographic techniques, owing to its distinct physical and chemical properties.
| Molecular weight | 100.04 |
|---|---|
| Linear formula | CF3CH2OH |
| Assay | ≥99.5% (GC) |
| Grade | puriss. |
| Boiling point | 77-80 °C(lit.) |
| Density | 1.373 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3(lit.) |
| Melting point | −44 °C(lit.) |
| Vapour pressure | 70 mmHg (25 °C) |
| Vapour density | 3.5 (vs air) |
| Autoignition temp | ~896 °F |
| Impurities tested | DNases, none detectedRNases, none detectedinsoluble matter, passes filter testphosphatases, none detectedproteases, none detected |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H318Causes serious eye damage
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 29 °C / 84.2 °F |
| Transport (UN / ADR) | UN 1986 3/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22-37/38-41 |
| Safety statements (S) | 26-36-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 42 % |
|---|---|
| Uv Absorption | λ: 260 nm Amax: ≤0.03λ: 280 nm Amax: ≤0.02 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethanol primarily used for?
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2,2,2-Trifluoroethanol is primarily used as a specialty solvent in organic synthesis, particularly for peptides and proteins, and as a building block for creating fluorinated organic compounds used in pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 2,2,2-Trifluoroethanol?
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The CAS number is 75-89-8 and the molecular formula is CF3CH2OH.
What grade and purity does Tech Serve Solutions supply for 2,2,2-Trifluoroethanol?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethanol at a minimum purity of 99.5% (GC), specified as puriss. grade. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product specifications.
What are the main safety concerns when handling 2,2,2-Trifluoroethanol?
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2,2,2-Trifluoroethanol is classified as Danger, with hazards including flammability (H226), acute toxicity (H301, H312, H331), skin irritation (H315), and serious eye damage (H318). It can also cause respiratory irritation (H335). Appropriate personal protective equipment, including safety shields, gloves, and respiratory protection, is essential.
How is 2,2,2-Trifluoroethanol packed and shipped by TSS?
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Tech Serve Solutions offers 2,2,2-Trifluoroethanol in various packaging options, including amber glass bottles suitable for solvents, and can accommodate specific solvent packaging requirements for export.
How can I request a quote or sample of 2,2,2-Trifluoroethanol?
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To request a quote or sample of 2,2,2-Trifluoroethanol, please use the contact form on our website or contact our sales team directly with your specific requirements.
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