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2,2,2-Trifluoroacetophenone

CAS 434-45-7CF3COC6H5Chemical Synthesis

2,2,2-Trifluoroacetophenone (CAS: 434-45-7), with the molecular formula C7H5F3O and a molecular weight of 174.12 g/mol, is a fluorinated ketone. This compound serves as a valuable building block in organic synthesis. Its notable applications include the creation of advanced fluorinated polymers, contributing to materials with enhanced thermal stability and desirable film-forming characteristics.

IUPAC
α,α,α-Trifluoroacetophenone,Phenyl trifluoromethyl ketone
Synonyms
434-45-7CF3COC6H5α,α,α-TrifluoroacetophenonePhenyl trifluoromethyl ketone
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2,2,2-Trifluoroacetophenone (CF3COC6H5) — chemical structure, CAS 434-45-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC7 to C8Carbonyl CompoundsChemical SynthesisKetones
01 /Applications

Fluorinated Polymer Synthesis

2,2,2-Trifluoroacetophenone is utilized in the synthesis of novel fluorinated polymers. These polymers are known for their high average molecular weights, excellent thermal stability, and good film-forming properties.

Organic Synthesis Intermediate

As a trifluoromethyl ketone, this compound acts as a versatile intermediate in various organic synthesis pathways. It enables the introduction of the trifluoromethyl group into complex molecules.

Building Block for Specialty Chemicals

This chemical serves as a foundational building block for the development of other specialised chemical compounds. Its unique structure lends itself to the creation of materials with specific performance attributes.

02 /Properties
Molecular weight174.12
Linear formulaCF3COC6H5
Assay99%
Boiling point165-166 °C(lit.)46-48 °C/14 mmHg(lit.)
Density1.24 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.458(lit.)
Application2,2,2-Trifluoroacetophenone was used in the synthesis of new fluorinated polymers, having high average molecular weight, high thermal stability and good film-forming properties1.
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point41 °C / 105.8 °F
Transport (UN / ADR)UN 1224C 3 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)10-36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
434-45-7
MDL number
MFCD00000420
PubChem substance
24846784
Beilstein registry
1866286
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,2,2-Trifluoroacetophenone used for?

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2,2,2-Trifluoroacetophenone is used as a building block in organic synthesis, particularly for creating fluorinated polymers with high thermal stability and good film-forming properties.

What is the CAS number and formula for 2,2,2-Trifluoroacetophenone?

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The CAS number is 434-45-7 and the linear formula is CF3COC6H5.

What grade and purity does Tech Serve Solutions supply for 2,2,2-Trifluoroacetophenone?

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Tech Serve Solutions supplies 2,2,2-Trifluoroacetophenone with a purity of 99%. This is a technical or research grade material, and TSS does not represent it as USP, BP, or EP grade.

How should 2,2,2-Trifluoroacetophenone be handled safely?

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2,2,2-Trifluoroacetophenone is a flammable liquid and vapour (H226), and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for full details.

Is 2,2,2-Trifluoroacetophenone available for export and how is it shipped?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. 2,2,2-Trifluoroacetophenone is classified as UN 1224C 3 / PGIII for transport.

How can I request a quote or sample of 2,2,2-Trifluoroacetophenone?

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To request a quote or sample, please contact our sales team through the website or by calling our direct line. Provide the product name and CAS number (434-45-7) for prompt service.

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