2,2,2-Trifluoroethyl vinyl ether
2,2,2-Trifluoroethyl vinyl ether (CAS: 406-90-6) is a volatile, flammable organic compound with the molecular formula C4H5F3O and a molecular weight of 126.08 g/mol. This acyclic ether and alkene serves as a valuable building block in organic synthesis. It is characterised by its refractive index of n20/D 1.320 and a density of 1.108 g/mL at 25°C, requiring storage at 2-8°C. Its primary utility lies in chemical synthesis and research applications.
- IUPAC
- (2,2,2-Trifluoroethoxy)ethene,Fluoroxene
- Synonyms
- 406-90-6C4H5F3O(2,2,2-Trifluoroethoxy)etheneFluoroxene

Organic Synthesis Intermediate
2,2,2-Trifluoroethyl vinyl ether is employed as a reactive intermediate in the synthesis of complex organic molecules. Its unique trifluoroethoxy group and vinyl functionality allow for diverse chemical transformations.
Fluorinated Compound Precursor
The compound serves as a precursor for introducing the 2,2,2-trifluoroethoxy moiety into various organic structures. This is particularly useful in the development of pharmaceuticals and agrochemicals where fluorination can impart desirable properties.
Research and Development
It is utilized in academic and industrial research laboratories for exploring novel reaction pathways and developing new fluorinated materials. Its distinct chemical properties make it a subject of interest in mechanistic studies.
| Molecular weight | 126.08 |
|---|---|
| Empirical formula | C4H5F3O |
| Assay | 97% |
| Density | 1.108 g/mL at 25 °C |
| Refractive index | n20/D 1.320 |
| Storage temperature | 2-8°C |


Hazard statements
- H225Highly flammable liquid and vapour
- H318Causes serious eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -28 °C / -18.4 °F |
| Transport (UN / ADR) | UN 3271 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 10-41 |
| Safety statements (S) | 16-26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethyl vinyl ether used for?
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2,2,2-Trifluoroethyl vinyl ether is primarily used as a building block in organic synthesis and as a precursor for fluorinated compounds in research and development.
What is the CAS number and molecular formula for 2,2,2-Trifluoroethyl vinyl ether?
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The CAS number is 406-90-6, and the molecular formula is C4H5F3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethyl vinyl ether with an assay of 97%. This product is not represented as USP, BP, or EP grade.
What are the primary safety concerns when handling 2,2,2-Trifluoroethyl vinyl ether?
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2,2,2-Trifluoroethyl vinyl ether is a highly flammable liquid and vapour (H225) and can cause serious eye damage (H318). Handle with appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, in a well-ventilated area away from ignition sources.
How is 2,2,2-Trifluoroethyl vinyl ether packaged and shipped?
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This product is classified under UN 3271, 3/PGII, indicating it is shipped as a flammable liquid. Packaging adheres to relevant transportation regulations for hazardous materials.
How can I request a quote or sample for 2,2,2-Trifluoroethyl vinyl ether?
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To request a quote or sample, please contact our sales department via the website or listed contact details, providing your requirements and shipping information.
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