2,2,2-Trifluoroethylamine hydrochloride
2,2,2-Trifluoroethylamine hydrochloride (CAS 373-88-6) is a valuable organic building block with the linear formula CF3CH2NH2 · HCl and a molecular weight of 135.52 g/mol. Supplied by Tech Serve Solutions with an assay of 98%, this amine salt is primarily used in chemical synthesis for the derivatization of carboxylic acids, forming stable trifluoroethylamide derivatives. Its unique trifluoromethyl group offers specific reactivity for advanced organic transformations.
- IUPAC
- 2-Amino-1,1,1-trifluoroethane hydrochloride
- Synonyms
- 373-88-6CF3CH2NH2 · HCl2-Amino-1,1,1-trifluoroethane hydrochloride
Derivatization of Carboxylic Acids
2,2,2-Trifluoroethylamine hydrochloride is employed to convert aqueous carboxylic acids into their corresponding 2,2,2-trifluoroethylamide derivatives. This reaction is a key step in certain analytical and synthetic methodologies.
Organic Synthesis Building Block
As a fluorinated amine salt, it serves as a versatile building block in organic synthesis. The trifluoromethyl moiety introduces unique electronic and steric properties into target molecules.
Research and Development
This compound is utilised in research laboratories for the development of new chemical entities and the exploration of novel synthetic routes, particularly in pharmaceutical and agrochemical research.
| Molecular weight | 135.52 |
|---|---|
| Linear formula | CF3CH2NH2 · HCl |
| Assay | 98% |
| Application | 2,2,2-Trifluoroethylamine hydrochloride was used in the derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative1. |
| Melting point | 220-222 °C (subl.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethylamine hydrochloride used for?
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2,2,2-Trifluoroethylamine hydrochloride is used in the derivatization of aqueous carboxylic acids to form 2,2,2-trifluoroethylamide derivatives and as a general building block in organic synthesis.
What are the CAS number and formula for 2,2,2-Trifluoroethylamine hydrochloride?
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The CAS number is 373-88-6 and the linear formula is CF3CH2NH2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethylamine hydrochloride with an assay of 98%. This is typically suitable for research and general chemical synthesis. We do not represent this product as USP, BP, or EP grade.
How should 2,2,2-Trifluoroethylamine hydrochloride be handled?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Ensure adequate ventilation as the compound may be harmful if inhaled, swallowed, or absorbed through the skin (H302, H312, H332).
Is 2,2,2-Trifluoroethylamine hydrochloride a controlled substance?
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Based on the provided data, there is no indication that 2,2,2-Trifluoroethylamine hydrochloride (CAS 373-88-6) is a controlled substance.
How is 2,2,2-Trifluoroethylamine hydrochloride packed and shipped?
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Tech Serve Solutions packs and ships fine chemicals, including 2,2,2-Trifluoroethylamine hydrochloride, in compliance with international regulations for hazardous materials. We are a global supplier and exporter.
How can I request a quote or sample for 2,2,2-Trifluoroethylamine hydrochloride?
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To request a quote or sample, please use the contact form on our website or email our sales department, specifying the product name and CAS number (373-88-6).
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