2,2,2-Trifluoroethylhydrazine solution
2,2,2-Trifluoroethylhydrazine solution (CAS: 5042-30-8) is an organic compound with the molecular formula CF3CH2NHNH2 and a molecular weight of 114.07 g/mol. This solution, typically at a 70 wt.% concentration in water, serves as a valuable reagent in chemical synthesis and analytical applications. It has been employed in studies of protein interactions and for the simultaneous determination of aldehydes and acetone in aqueous samples.
- Synonyms
- 5042-30-8CF3CH2NHNH2

Biochemical Research Reagent
2,2,2-Trifluoroethylhydrazine has been utilised in biochemical studies, specifically for investigating the interaction of myoglobin with heme proteins.
Analytical Chemistry
This compound can be used in analytical methods for the simultaneous determination of aldehydes and acetone, particularly within aqueous environments.
Organic Synthesis Building Block
As a hydrazine derivative, it functions as a versatile building block in organic synthesis, enabling the construction of more complex molecular structures.
| Molecular weight | 114.07 |
|---|---|
| Linear formula | CF3CH2NHNH2 |
| Density | 1.294 g/mL at 25 °C |
| Refractive index | n20/D 1.361 |
| Concentration | 70 wt. % in H2O |
| Application | 2,2,2-trifluoroethylhydrazine was added to myoglobin to study its interaction with heme protein1. It was also used to determine aldehydes and acetone simultaneously in water2. |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoroethylhydrazine solution used for?
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2,2,2-Trifluoroethylhydrazine solution is used as a reagent in biochemical research for studying protein interactions and in analytical chemistry for the determination of aldehydes and acetone. It also serves as a building block in organic synthesis.
What are the CAS number and chemical formula for 2,2,2-Trifluoroethylhydrazine solution?
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The CAS number is 5042-30-8 and the linear chemical formula is CF3CH2NHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,2-Trifluoroethylhydrazine solution typically at 70 wt.% in H2O. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or any pharmacopoeial grade.
How should 2,2,2-Trifluoroethylhydrazine solution be handled safely?
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2,2,2-Trifluoroethylhydrazine solution is classified with GHS06 symbol and 'Danger' signal word. It carries hazard statements H302, H312, and H331, indicating it is harmful if swallowed, in contact with skin, and if inhaled. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., type ABEK respirator filter), must be used. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is 2,2,2-Trifluoroethylhydrazine solution a controlled substance?
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The provided data does not indicate that 2,2,2-Trifluoroethylhydrazine solution is a controlled substance.
How is 2,2,2-Trifluoroethylhydrazine solution packed and shipped?
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2,2,2-Trifluoroethylhydrazine solution is packed and shipped according to relevant regulations for hazardous materials, including UN 1993 classification for transport.
How can I request a quote or sample?
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To request a quote or a sample of 2,2,2-Trifluoroethylhydrazine solution, please contact our sales team through the TSS website or by phone.
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