Chloromethyl 4-chlorophenyl sulfide
Chloromethyl 4-chlorophenyl sulfide (CAS: 7205-90-5, Formula: ClC6H4SCH2Cl, MW: 193.09) is a key organic building block utilised in chemical synthesis. It serves as a reactive alkylating agent for introducing the (4-chlorophenylthio)methyl group. This compound has been instrumental in research studies, including investigations into the solvolysis of related sulfides and the synthesis of heterocyclic compounds.
Research in Solvolysis Studies
Chloromethyl 4-chlorophenyl sulfide has been employed in kinetic and mechanistic studies of the solvolysis of chloromethyl phenyl sulfide derivatives in various hydroxylic solvents, providing insights into reaction pathways.
Synthesis of Organic Intermediates
This compound acts as a crucial starting material in the synthesis of specific organic molecules, such as (4-chlorophenylthio)methyl acetate, serving as a precursor in multi-step synthetic routes.
Alkylating Agent in Heterocyclic Synthesis
It functions as an effective alkylating reagent in the preparation of complex organic structures, notably in the microwave-assisted synthesis of 2-amino-imidazo[1,2-a]pyridine derivatives.
| Molecular weight | 193.09 |
|---|---|
| Linear formula | ClC6H4SCH2Cl |
| Assay | 97% |
| Boiling point | 128-129 °C/12 mmHg(lit.) |
| Density | 1.348 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.6065(lit.) |
| Application | Chloromethyl 4-chlorophenyl sulfide was used to study the solvolysis of chloromethyl phenyl sulfide [(phenylthio)methyl chloride] and its p-chloro-derivative in a wide range of hydroxylic solvents1. It was used as starting reagent in the synthesis of (4-chlorophenylthio) methyl acetate2. It was used as alkylating reagent in microwave-assisted synthesis of 2-amino-imidazo[1,2-a]pyridine derivatives3. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloromethyl 4-chlorophenyl sulfide used for?
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Chloromethyl 4-chlorophenyl sulfide is used as a building block in organic synthesis, for studying solvolysis reactions, and as an alkylating agent in the synthesis of compounds like 2-amino-imidazo[1,2-a]pyridine derivatives.
What are the CAS number and formula for Chloromethyl 4-chlorophenyl sulfide?
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The CAS number is 7205-90-5, and the linear formula is ClC6H4SCH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloromethyl 4-chlorophenyl sulfide with an assay of 97%. This is a technical/research grade material; TSS does not represent it as USP, BP, or EP grade.
How should Chloromethyl 4-chlorophenyl sulfide be handled safely?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, goggles, face shield, and a suitable respirator. Ensure adequate ventilation and refer to the Safety Data Sheet for full handling instructions.
How is Chloromethyl 4-chlorophenyl sulfide packaged and exported?
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Chloromethyl 4-chlorophenyl sulfide is packaged in compliance with transport regulations (UN 3265 8 / PGII) and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for Chloromethyl 4-chlorophenyl sulfide?
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To request a quote or a sample, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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