Chloromethyl methyl sulfide
Chloromethyl methyl sulfide (CAS 2373-51-5), with the chemical formula CH3SCH2Cl and a molecular weight of 96.58 g/mol, is a valuable reagent in organic synthesis. It functions as a methylthiomethylating agent for various organic compounds, including carbonyls and aromatics. Additionally, it serves as a methylene transfer reagent in specific catalytic processes, facilitating complex molecular constructions. Its applications are primarily within chemical synthesis and research laboratories.
- IUPAC
- Chlorodimethyl sulfide
Methylthiomethylating Reagent
Chloromethyl methyl sulfide is employed as a methylthiomethylating agent for the derivatization of carbonyl and aromatic compounds in organic synthesis. This allows for the introduction of the methylthiomethyl group, which can serve as a protecting group or a handle for further transformations.
Methylene Transfer Reagent
This compound acts as a methylene transfer reagent in iron(II)-mediated cyclopropanation reactions. This application is significant in constructing cyclopropane rings, which are found in various natural products and pharmaceuticals.
Protecting and Derivatizing Reagent
As a reagent in the category of protecting and derivatizing agents, Chloromethyl methyl sulfide is utilized to selectively modify functional groups. Its specific reactivity makes it suitable for protecting alcohols and other nucleophiles during multi-step synthetic sequences.
| Molecular weight | 96.58 |
|---|---|
| Linear formula | CH3SCH2Cl |
| Assay | 95% |
| Boiling point | 105 °C(lit.) |
| Density | 1.153 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.498(lit.) |
| Storage temperature | 2-8°C |
| Application | Methylthiomethylating reagent for carbonyl1 and aromatic2 compounds. Methylene transfer reagent for iron(II) mediated cyclopropanation.3 |
Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 17 °C / 62.6 °F |
| Transport (UN / ADR) | UN 1993BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-37 |
| Safety statements (S) | 9-16-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloromethyl methyl sulfide used for?
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Chloromethyl methyl sulfide is primarily used as a methylthiomethylating reagent for carbonyl and aromatic compounds, and as a methylene transfer reagent in iron(II)-mediated cyclopropanation reactions.
What is the CAS number and chemical formula for Chloromethyl methyl sulfide?
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The CAS number is 2373-51-5 and the chemical formula is CH3SCH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloromethyl methyl sulfide with an assay of 95%. This product is suitable for research and general chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
How should Chloromethyl methyl sulfide be handled safely?
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Chloromethyl methyl sulfide is a highly flammable liquid and vapour (H225). Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Keep away from heat, sparks, and open flames. It is classified with GHS02 symbol and 'Danger' signal word.
How is Chloromethyl methyl sulfide packed and shipped?
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Chloromethyl methyl sulfide is packaged in compliance with regulations for hazardous materials, including UN 1993 classification. We are experienced exporters and can arrange global shipment according to your requirements.
How can I request a sample or quote for Chloromethyl methyl sulfide?
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To request a sample or a quote for Chloromethyl methyl sulfide, please use the contact form on our website or contact our sales team directly with your specific requirements.
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