1-Boc-piperazine
1-Boc-piperazine (CAS: 57260-71-6, C9H18N2O2) is a valuable organic compound with a molecular weight of 186.25 g/mol. This piperazine derivative serves as a key building block in chemical synthesis, particularly for the preparation of monosubstituted piperazines. It finds utility in the development of complex molecules, including pharmaceutical intermediates.
- IUPAC
- tert-Butyl piperazine-1-carboxylate
- Synonyms
- tert-Butyl piperazine-1-carboxylate
Synthesis of Monosubstituted Piperazines
1-Boc-piperazine is a crucial intermediate for preparing monosubstituted piperazine derivatives. This is essential in multi-step synthetic routes for advanced organic compounds.
Pharmaceutical Intermediate Development
The compound is employed in the synthesis of biologically active molecules, such as indazole DNA gyrase inhibitors. Its structure allows for targeted functionalisation in drug discovery programmes.
Heterocyclic Building Block
As a heterocyclic building block, 1-Boc-piperazine offers a protected piperazine core for incorporation into diverse molecular architectures.
| Molecular weight | 186.25 |
|---|---|
| Empirical formula | C9H18N2O2 |
| Assay | 97% |
| Application | Preparation of monosubstituted piperazines, e.g. in the synthesis of indazole DNA gyrase inhibitors.1 |
| Melting point | 43-47 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-piperazine used for?
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1-Boc-piperazine is primarily used as a building block in chemical synthesis for preparing monosubstituted piperazines, finding applications in the development of pharmaceutical intermediates like indazole DNA gyrase inhibitors.
What are the CAS number and formula for 1-Boc-piperazine?
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The CAS number for 1-Boc-piperazine is 57260-71-6, and its molecular formula is C9H18N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-piperazine with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 1-Boc-piperazine be handled?
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1-Boc-piperazine is classified as a Warning substance, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment: a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is 1-Boc-piperazine packed and shipped?
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1-Boc-piperazine is carefully packed according to industry standards for safe transport. As a global supplier and exporter, Tech Serve Solutions adheres to all regulations for international shipping.
How can I request a sample or quote for 1-Boc-piperazine?
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To request a sample or a quote for 1-Boc-piperazine, please contact our sales team through the website or by calling us directly. Provide your specific requirements for prompt assistance.
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