L-Penicillamine
L-Penicillamine (CAS: 1113-41-3) is a chiral amino acid derivative with a molar mass of 149.21 g/mol. It functions as a potent metal-chelating agent. Its structure, featuring a thiol group and a chiral centre, makes it valuable in chemical biology and synthesis. L-Penicillamine is primarily utilised for its therapeutic applications in managing conditions related to copper and heavy metal accumulation.
- IUPAC
- 3,3-Dimethyl-L-cysteine,3-Mercapto-L-valine,L-(+)-2-Amino-3-mercapto-3-methylbutanoic acid β,β-Dimethyl-L-cysteine
- Synonyms
- 3,3-Dimethyl-L-cysteine3-Mercapto-L-valineL-(+)-2-Amino-3-mercapto-3-methylbutanoic acidβ,β-Dimethyl-L-cysteine
Metal Chelation Therapy
L-Penicillamine is a key therapeutic agent for chelating excess copper in Wilson's disease and for treating heavy metal poisoning, such as lead or mercury poisoning. It binds to these metals, facilitating their excretion from the body.
Chemical Synthesis
As a building block, L-Penicillamine is employed in chemical synthesis, particularly in the development of novel pharmaceutical intermediates and research chemicals. Its unique thiol and amino functionalities allow for diverse derivatization.
Biochemical Research
In chemical biology, L-Penicillamine serves as a tool for studying metal-dependent enzymatic processes and for developing modified peptides. Its ability to interact with metals is exploited in various biochemical assays.
| Molecular weight | 149.21 |
|---|---|
| Linear formula | (CH3)2C(SH)CH(NH2)CO2H |
| Assay | 99% |
| Optical activity | [α]24/D +61.9°, c = 0.5 in 1 M NaOH |
| Application | Metal-chelating agent |
| Melting point | 206 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Penicillamine used for?
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L-Penicillamine is used as a metal-chelating agent, particularly in the treatment of Wilson's disease and heavy metal poisoning. It also finds applications in chemical synthesis and biochemical research.
What is the CAS number and formula for L-Penicillamine?
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The CAS number for L-Penicillamine is 1113-41-3. Its linear formula is (CH3)2C(SH)CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Penicillamine with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should L-Penicillamine be handled?
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L-Penicillamine is classified as a warning substance, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, such as a dust mask (N95), eyeshields, and gloves, should be worn during handling.
Is L-Penicillamine a controlled substance?
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The provided data does not indicate that L-Penicillamine is a controlled substance.
How is L-Penicillamine packaged and shipped?
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L-Penicillamine is carefully packaged to maintain its integrity during transit. Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for L-Penicillamine?
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To request a sample or quote for L-Penicillamine, please contact our sales department via the website or your dedicated account manager.
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