L-Norleucine
L-Norleucine (CAS: 327-57-1), a non-proteinogenic amino acid with the formula CH3(CH2)3CH(NH2)CO2H and a molecular weight of 131.17 g/mol, is supplied by Tech Serve Solutions. This compound is valuable in various scientific applications, including biochemical research, chemical synthesis, and peptide chemistry. Its utility extends to cell biology and nutrition research, making it a versatile reagent for laboratory investigations.
- IUPAC
- (S)-(+)-2-Aminohexanoic acid,(S)-2-Aminocaproic acid
- Synonyms
- (S)-(+)-2-Aminohexanoic acid(S)-2-Aminocaproic acid

Peptide Synthesis
L-Norleucine serves as an unnatural amino acid in the synthesis of peptides and peptidomimetics. It can be incorporated to study structure-activity relationships or to confer specific properties to peptide-based molecules.
Biochemical Research
As a biochemical reagent, L-Norleucine is utilized in studies involving amino acid metabolism and protein synthesis. Its non-natural occurrence makes it a useful tool for tracking or inhibiting biological pathways.
Chemical Synthesis Intermediate
This compound can act as a building block in the synthesis of more complex organic molecules. Its amino and carboxylic acid functionalities offer versatile reaction sites for various chemical transformations.
Nutrition and Metabolic Studies
L-Norleucine is employed in research contexts to investigate nutritional requirements and metabolic processes, particularly where the effects of non-proteinogenic amino acids are of interest.
| Molecular weight | 131.17 |
|---|---|
| Linear formula | CH3(CH2)3CH(NH2)CO2H |
| Assay | ≥98% (TLC) |
| Suitability | suitable for amino acid analysis |
| Melting point | >300 °C(lit.) |

Hazard statements
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Norleucine used for?
+
L-Norleucine is used in peptide synthesis, biochemical research, chemical synthesis, and nutrition and metabolic studies. It is particularly useful as an unnatural amino acid in research.
What are the CAS number and formula for L-Norleucine?
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The CAS number for L-Norleucine is 327-57-1, and its linear formula is CH3(CH2)3CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply for L-Norleucine?
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Tech Serve Solutions supplies L-Norleucine with an assay of ≥98% (TLC). This product is suitable for amino acid analysis. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.
How should L-Norleucine be handled safely?
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L-Norleucine is classified as a skin sensitizer (H317) and requires careful handling. Personnel should wear appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves, in well-ventilated areas. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is L-Norleucine shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including L-Norleucine, and can accommodate international shipping requests.
How can I request a quote or sample for L-Norleucine?
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To request a quote or a sample of L-Norleucine, please contact our sales department through the TSS website or by phone.
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