1-Boc-azetidine-3-carboxylic acid
1-Boc-azetidine-3-carboxylic acid (CAS: 142253-55-2), with the molecular formula C9H15NO4 and a molecular weight of 201.22 g/mol, is a valuable building block in organic synthesis. This compound is particularly useful in peptide chemistry and the development of unnatural amino acid derivatives. Its structure allows for controlled introduction of azetidine moieties into complex molecules, facilitating advancements in chemical biology and pharmaceutical research.

Peptide Synthesis
1-Boc-azetidine-3-carboxylic acid serves as a specialised building block for incorporating non-proteinogenic amino acid residues into peptide chains. This enables the creation of peptidomimetics with potentially enhanced stability or novel biological activities.
Chemical Biology Research
This compound is employed in chemical biology to construct modified peptides or small molecules for investigating biological pathways. Its unique azetidine ring can modulate molecular conformation and receptor binding properties.
Medicinal Chemistry
As an unnatural amino acid derivative, it finds application in medicinal chemistry for the synthesis of drug candidates. The azetidine scaffold can confer specific structural constraints or improve pharmacokinetic properties.
Organic Synthesis Intermediate
Beyond its use in peptide and medicinal chemistry, 1-Boc-azetidine-3-carboxylic acid functions as a versatile intermediate for a range of organic synthesis projects requiring the azetidine-3-carboxylate motif.
| Molecular weight | 201.22 |
|---|---|
| Empirical formula | C9H15NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-azetidine-3-carboxylic acid used for?
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1-Boc-azetidine-3-carboxylic acid is primarily used as a building block in peptide synthesis, for creating unnatural amino acid derivatives, and in chemical biology and medicinal chemistry research.
What is the CAS number and molecular formula for 1-Boc-azetidine-3-carboxylic acid?
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The CAS number for 1-Boc-azetidine-3-carboxylic acid is 142253-55-2, and its molecular formula is C9H15NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-azetidine-3-carboxylic acid with an assay of ≥98.0% (TLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Boc-azetidine-3-carboxylic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Users should consult the Safety Data Sheet (SDS) for detailed hazard information.
Is 1-Boc-azetidine-3-carboxylic acid a controlled substance?
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Based on the provided data, there is no indication that 1-Boc-azetidine-3-carboxylic acid is a controlled substance.
How is 1-Boc-azetidine-3-carboxylic acid packed and shipped?
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1-Boc-azetidine-3-carboxylic acid is carefully packed for safe handling and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 1-Boc-azetidine-3-carboxylic acid?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through the website or designated contact channels.
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