1-Boc-L-azetidine-2-carboxylic acid

CAS 51077-14-6C9H15NO4Chemical Synthesis

1-Boc-L-azetidine-2-carboxylic acid (CAS: 51077-14-6, Formula: C9H15NO4) is a chiral building block with a molecular weight of 201.22 g/mol. This unnatural amino acid derivative is widely employed in chemical synthesis and peptide chemistry. Its protected azetidine ring offers unique structural motifs for incorporation into peptides and other complex organic molecules, facilitating drug discovery and development research.

IUPAC: 1-Boc-(S)-azetidine-2-carboxylic acid

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1-Boc-L-azetidine-2-carboxylic acid (C9H15NO4) — chemical structure, CAS 51077-14-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisOthersPeptide Chemistry

01 /Applications

Peptide Synthesis

Incorporated into peptide chains as an unnatural amino acid to modify structure and function. Useful for creating peptidomimetics and analogues with enhanced stability or novel biological activities.

Organic Synthesis

Serves as a chiral building block for the construction of complex organic molecules. The azetidine ring provides a strained cyclic structure that can be leveraged in various synthetic strategies.

Drug Discovery

Utilised in medicinal chemistry research for the development of new therapeutic agents. Its unique structural features can contribute to novel pharmacophores.

Chemical Biology

Employed in studies exploring biological systems and pathways. Can be used to create labelled probes or modified biomolecules for research purposes.

02 /Properties

Molecular weight	201.22
Empirical formula	C9H15NO4
Assay	≥98.0% (TLC)
Optical activity	[α]/D -120.0±2.0°, c = 1 in methanol

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51077-14-6

MDL number

MFCD01321011

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-Boc-L-azetidine-2-carboxylic acid used for?

1-Boc-L-azetidine-2-carboxylic acid is primarily used as a chiral building block in organic synthesis, particularly in peptide chemistry and drug discovery research for creating novel molecular structures.

What is the CAS number and formula for 1-Boc-L-azetidine-2-carboxylic acid?

The CAS number is 51077-14-6 and the empirical formula is C9H15NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1-Boc-L-azetidine-2-carboxylic acid with a purity of ≥98.0% (TLC). TSS does not represent this product as USP/BP/EP grade.

How should 1-Boc-L-azetidine-2-carboxylic acid be handled?

This compound is a warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust.