1-Boc-indole-5-boronic acid pinacol ester

CAS 777061-36-6C19H26BNO4Chemical Synthesis

1-Boc-indole-5-boronic acid pinacol ester (CAS: 777061-36-6; C19H26BNO4) is a valuable organometallic reagent featuring a protected indole core and a boronate ester moiety. This compound is primarily utilised in organic synthesis, particularly in cross-coupling reactions. Its protected indole structure allows for selective functionalization, making it a key building block for complex molecular architectures in research and development.

IUPAC: 1-Boc-5-indoleboronic acid pinacol ester,5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-Boc-indole
Synonyms: 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-Boc-indole

Email us

1-Boc-indole-5-boronic acid pinacol ester (C19H26BNO4) — chemical structure, CAS 777061-36-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

As a boronate ester, this compound is an effective coupling partner in Suzuki-Miyaura reactions for the formation of carbon-carbon bonds. It is used to introduce the protected indole-5-yl group onto various organic scaffolds.

Medicinal Chemistry and Drug Discovery

The indole scaffold is prevalent in many biologically active molecules. This reagent serves as a precursor for synthesising novel indole-containing compounds with potential therapeutic applications.

Materials Science

Indole derivatives can be incorporated into organic electronic materials. This boronate ester offers a route to functionalized indoles for applications in areas such as organic semiconductors or optoelectronic devices.

Advanced Organic Synthesis

The Boc-protected indole allows for controlled synthetic transformations, enabling chemists to build complex molecules step-by-step with regioselectivity and chemoselectivity.

02 /Properties

Molecular weight	343.23
Empirical formula	C19H26BNO4
Assay	97%
Melting point	131-136 °C(lit.)

03 /Safety & handling

Hazard statements

H413May cause long-lasting harmful effects to aquatic life

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

777061-36-6

MDL number

MFCD05663895

PubChem substance

24883088

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-Boc-indole-5-boronic acid pinacol ester used for?

1-Boc-indole-5-boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to introduce a protected indole moiety into complex molecules for medicinal chemistry, materials science, and research.

What is the CAS number and molecular formula?

The CAS number is 777061-36-6, and the molecular formula is C19H26BNO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of 97%. It is typically considered a research or technical grade chemical, and we do not represent it as USP, BP, or EP grade.

What are the safety and handling precautions?

This compound may cause long-lasting harmful effects to aquatic life (H413). Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling. It has a melting point of 131-136 °C.

How is this chemical shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we ensure appropriate packaging and documentation for the safe and compliant shipment of 1-Boc-indole-5-boronic acid pinacol ester worldwide.

How can I request a quote or sample?

To request a quote or sample for 1-Boc-indole-5-boronic acid pinacol ester, please contact our sales department via the website or direct inquiry, providing your specific requirements.