4-(Trifluoromethyl)aniline
4-(Trifluoromethyl)aniline (CAS 455-14-1), with the molecular formula CF3C6H4NH2 and a molecular weight of 161.12 g/mol, is a key organic building block. This compound is utilised in chemical synthesis, particularly in the preparation of various aniline derivatives. Its distinctive trifluoromethyl group makes it a valuable intermediate for introducing fluorine into organic molecules, finding application in the pharmaceutical and agrochemical industries. TSS supplies this chemical with an assay of 99%.
- IUPAC
- α,α,α-Trifluoro-p-toluidine,4-Aminobenzotrifluoride
Synthetic Intermediate
4-(Trifluoromethyl)aniline serves as a crucial intermediate in organic synthesis. It is employed in the preparation of more complex molecules, including pharmaceuticals and agrochemicals, where the trifluoromethyl moiety is desired.
Building Block for Aniline Derivatives
This compound is utilised as a foundational building block for the synthesis of substituted anilines. Its specific structure allows for further functionalization, leading to a diverse range of chemical compounds.
Research and Development
In research settings, 4-(Trifluoromethyl)aniline is used in the development of novel chemical entities and the exploration of new synthetic pathways. Its reliable availability from TSS supports ongoing R&D efforts.
| Molecular weight | 161.12 |
|---|---|
| Linear formula | CF3C6H4NH2 |
| Assay | 99% |
| Boiling point | 83 °C/12 mmHg(lit.) |
| Density | 1.283 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.483(lit.) |
| Application | 4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines1. It was also used as a synthetic building block2. |
Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | UN 2810 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-36-50/53 |
| Safety statements (S) | 26-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)aniline used for?
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4-(Trifluoromethyl)aniline is used as a synthetic intermediate and a building block for various organic compounds, including substituted anilines. It is particularly valuable in the synthesis of fluorinated molecules for pharmaceutical and agrochemical applications.
What is the CAS number and molecular formula for 4-(Trifluoromethyl)aniline?
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The CAS number for 4-(Trifluoromethyl)aniline is 455-14-1, and its molecular formula is CF3C6H4NH2.
What grade and purity does Tech Serve Solutions supply for 4-(Trifluoromethyl)aniline?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)aniline with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 4-(Trifluoromethyl)aniline be handled safely?
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4-(Trifluoromethyl)aniline is classified as dangerous. It is toxic if swallowed, causes serious eye irritation, and is very toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation and avoid release into the environment.
Is 4-(Trifluoromethyl)aniline a controlled substance?
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The provided data does not indicate that 4-(Trifluoromethyl)aniline is a controlled substance. However, users should always verify local regulations.
How is 4-(Trifluoromethyl)aniline packed, shipped, and exported?
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As a specialist global supplier and exporter, TSS ensures that 4-(Trifluoromethyl)aniline is packed, shipped, and exported in compliance with all relevant international regulations for hazardous materials.
How can I request a quote or sample of 4-(Trifluoromethyl)aniline?
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To request a quote or a sample of 4-(Trifluoromethyl)aniline, please contact the Tech Serve Solutions sales team through our website or by phone.
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