4-(Trifluoromethyl)-1H-pyrazole
4-(Trifluoromethyl)-1H-pyrazole (CAS: 52222-73-8; Formula: C4H3F3N2; Molar Mass: 136.08 g/mol) is a fluorinated heterocyclic building block. Its pyrazole core and trifluoromethyl substituent make it a valuable intermediate in organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. The compound's reactivity allows for diverse chemical transformations, enabling the construction of complex molecular architectures.
- IUPAC
- 4-Trifluoromethylpyrazole
Pharmaceutical Synthesis
Used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), leveraging its pyrazole and trifluoromethyl functionalities for drug discovery and development.
Agrochemical Development
A versatile building block for creating new pesticides, herbicides, and fungicides, where the trifluoromethyl group can enhance biological activity and stability.
Material Science
Explored for its potential use in the development of functional materials due to the unique electronic properties conferred by the trifluoromethyl substituent.
Organic Synthesis Research
Serves as a fundamental reagent in academic and industrial research for constructing complex heterocyclic compounds and exploring novel synthetic methodologies.
| Molecular weight | 136.08 |
|---|---|
| Empirical formula | C4H3F3N2 |
| Assay | 95% |
| Melting point | 73-78 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)-1H-pyrazole used for?
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4-(Trifluoromethyl)-1H-pyrazole is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and functional materials.
What are the CAS number and molecular formula of 4-(Trifluoromethyl)-1H-pyrazole?
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The CAS number is 52222-73-8 and the molecular formula is C4H3F3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)-1H-pyrazole with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the primary hazards associated with 4-(Trifluoromethyl)-1H-pyrazole?
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This compound is classified with GHS06 symbol and 'Danger' signal word. It is harmful if swallowed (H301), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335).
How is 4-(Trifluoromethyl)-1H-pyrazole packed and shipped?
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4-(Trifluoromethyl)-1H-pyrazole is shipped as UN 2811, Class 6.1, Packing Group III, according to ADR regulations. TSS is a specialist global supplier and exporter.
How can I request a sample or quote for 4-(Trifluoromethyl)-1H-pyrazole?
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Please contact the Tech Serve Solutions sales team directly via our website or by phone to request a sample or obtain a quotation.
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