1,3,3-Trimethyl-2-methyleneindoline
1,3,3-Trimethyl-2-methyleneindoline (CAS: 118-12-7), also known as Fischer's base, is an organic compound with the molecular formula C12H15N and a molecular weight of 173.25 g/mol. This indole derivative serves as a key building block in chemical synthesis, particularly in the preparation of photochromic dyes and polymers. Its reactivity makes it valuable for various cycloaddition reactions, contributing to the development of advanced materials and specialised chemical products.
- IUPAC
- 2-Methylene-1,3,3-trimethylindoline,Fischer base,NSC 66176
- Synonyms
- 118-12-72-Methylene-1,3,3-trimethylindolineFischer baseNSC 66176
Cycloaddition Reactions
This compound is utilised as a reactant in various cycloaddition reactions, enabling the formation of complex cyclic structures in organic synthesis.
Photochromic Dye Synthesis
It is employed in the preparation of red photochromic dyes, which change colour upon exposure to light. This application is significant in the development of light-sensitive materials.
Photochromic Polymer Development
The compound is used in the synthesis of photochromic homopolymers through ring-opening metathesis polymerization, leading to materials with tunable optical properties.
| Molecular weight | 173.25 |
|---|---|
| Empirical formula | C12H15N |
| Assay | 97% |
| Boiling point | 248 °C(lit.) |
| Density | 0.979 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.577(lit.) |
| Application | Reactant for:• Cycloaddition reactions1• Preparation of red photochromic dyes2• Synthesis of photochromic homopolymers via ring-opening metathesis polymerization3 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-38-50/53 |
| Safety statements (S) | 28-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3,3-Trimethyl-2-methyleneindoline used for?
+
1,3,3-Trimethyl-2-methyleneindoline is used as a reactant in cycloaddition reactions, for the preparation of red photochromic dyes, and for the synthesis of photochromic homopolymers via ring-opening metathesis polymerization.
What are the CAS number and molecular formula for 1,3,3-Trimethyl-2-methyleneindoline?
+
The CAS number is 118-12-7 and the molecular formula is C12H15N.
What grade and purity does Tech Serve Solutions supply for 1,3,3-Trimethyl-2-methyleneindoline?
+
Tech Serve Solutions supplies 1,3,3-Trimethyl-2-methyleneindoline with an assay of 97%. This is a technical/research grade and TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety hazards associated with 1,3,3-Trimethyl-2-methyleneindoline?
+
This compound is classified as harmful if swallowed (H302), causes skin irritation (H315), and is very toxic to aquatic life (H400). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used, and it should be handled in accordance with safety statements P273, P280, P301+P312, P302+P352, P332+P313, and P391.
How is 1,3,3-Trimethyl-2-methyleneindoline typically packed and shipped?
+
As a global supplier and exporter, Tech Serve Solutions ensures that 1,3,3-Trimethyl-2-methyleneindoline is packed and shipped in compliance with all relevant regulations, including those for hazardous materials (UN 3082, Class 9, Packing Group III).
How can I request a sample or quote for 1,3,3-Trimethyl-2-methyleneindoline?
+
To request a sample or a quote for 1,3,3-Trimethyl-2-methyleneindoline, please contact our sales department through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis