1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril
1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril (CAS: 51592-06-4) is a complex organic compound with the molecular formula C16H10Cl4N4O2 and a molecular weight of 432.09 g/mol. It functions primarily as an iodination reagent, acting as an oxidative agent in various chemical synthesis applications. This compound is also recognised for its role in protein modification and structural analysis within molecular biology and proteomics research.
- IUPAC
- Iodo-Gen®,NSC 4462
- Synonyms
- 6-Tetrachloro-3α,6α-diphenylglycourilC16H10Cl4N4O2Iodo-Gen®NSC 4462

Iodination Reagent
This compound serves as an effective iodination reagent, facilitating the introduction of iodine into other molecules. It is particularly useful as an oxidative agent in radioiodination processes.
Chemical Synthesis
Used in broader chemical synthesis, 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril participates in C-X bond formation, specifically halogenation. It has also been employed in the oxidation of urazoles.
Protein Modification and Analysis
In molecular biology and proteomics, this reagent is utilised for protein modification and structural analysis. Its ability to introduce specific chemical changes aids in understanding protein function and structure.
Comparative Studies
It has been involved in comparative studies with other reagents, such as chloramine-T, to evaluate and understand different oxidative mechanisms in chemical reactions.
| Molecular weight | 432.09 |
|---|---|
| Empirical formula | C16H10Cl4N4O2 |
| Storage temperature | 2-8°C |
| Application | Iodination reagent used in radioiodination acting as an oxidative agent1,2Reagent involved in comparison studies with chloramine-T3Reagent used for oxidation of urazoles4 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril used for?
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1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is primarily used as an iodination reagent, acting as an oxidative agent in radioiodination, chemical synthesis, and protein modification studies.
What are the CAS number and formula for this compound?
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The CAS number is 51592-06-4, and the empirical formula (Hill notation) is C16H10Cl4N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and purity are detailed in the product specifications; it is not supplied as USP, BP, or EP grade.
What are the safety and handling precautions for 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril?
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This compound is classified as a Warning, with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Store at 2-8°C.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and adherence to all shipping regulations for safe and efficient delivery worldwide.
How can I request a sample or a quote for 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril?
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To request a sample or a quote, please contact our sales team through the website or by calling our main office. Provide the product name and CAS number (51592-06-4) for prompt service.
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