Histamine dihydrochloride
Histamine dihydrochloride (CAS: 56-92-8), with the chemical formula C5H9N3 · 2HCl and a molecular weight of 184.07 g/mol, is a stable salt form of the biogenic amine histamine. It is a vital compound widely utilised in biochemical research, physiological studies, and as a building block in chemical synthesis. This substance serves as a key reagent in understanding histamine's biological roles and related physiological pathways.
- IUPAC
- 2-(4-Imidazolyl)ethylamine dihydrochloride,Histamini dihydrochloridum
- Synonyms
- 2-(4-Imidazolyl)ethylamine dihydrochlorideHistamini dihydrochloridum

Biochemical Research Reagent
Histamine dihydrochloride is extensively used in research laboratories to investigate the physiological effects of histamine, including its role in allergic responses and neurotransmission. It serves as a standard in pharmacological assays.
Chemical Synthesis Intermediate
As a versatile heterocyclic building block, this compound is employed in the synthesis of more complex organic molecules and potential pharmaceutical candidates. Its reactive nature allows for various chemical transformations.
Analytical Standard
It can be utilised as an analytical standard in chromatographic techniques and other analytical methods requiring a precise concentration of histamine for calibration or quantification.
| Molecular weight | 184.07 |
|---|---|
| Empirical formula | C5H9N3 · 2HCl |
| Assay | 98% |
| Melting point | 249-252 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pharmacopeia | testing conforms to Pharmacopeia |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Histamine dihydrochloride used for?
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Histamine dihydrochloride is primarily used as a biochemical research reagent to study histamine's physiological roles, as an intermediate in chemical synthesis, and as an analytical standard.
What is the CAS number and chemical formula for Histamine dihydrochloride?
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The CAS number is 56-92-8 and the chemical formula is C5H9N3 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Histamine dihydrochloride with an assay of 98%. This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
What are the main safety hazards associated with Histamine dihydrochloride?
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Histamine dihydrochloride is a danger. It causes skin irritation (H315), may cause an allergic skin reaction (H317), causes serious eye irritation (H319), may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334), and may cause respiratory irritation (H335).
How is Histamine dihydrochloride packed and exported?
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Histamine dihydrochloride is carefully packed to ensure stability and safety during transport. As a global supplier, Tech Serve Solutions is experienced in exporting chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a quote or sample for Histamine dihydrochloride?
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To request a quote or a sample of Histamine dihydrochloride, please contact our sales team through the website or by phone. Specify the required quantity and your delivery details.
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