4-(Trifluoromethoxy)phenylboronic acid pinacol ester
4-(Trifluoromethoxy)phenylboronic acid pinacol ester (CAS 474709-28-9, C13H16BF3O3) is a specialised organoboron compound with a molecular weight of 288.07 g/mol. It is a stable, crystalline solid. This boronate ester serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions for the formation of carbon-carbon bonds. Its trifluoromethoxy group offers unique electronic properties for advanced material and pharmaceutical research.
- IUPAC
- 4,4,5,5-Tetramethyl-2-(4-(trifluoromethoxy)phenyl)-1,3,2-dioxaborolane
- Synonyms
- 4,4,5,5-Tetramethyl-2-(4-(trifluoromethoxy)phenyl)-1,3,2-dioxaborolane
Suzuki-Miyaura Coupling Reagent
Utilised as a coupling partner in Suzuki-Miyaura reactions to introduce the 4-(trifluoromethoxy)phenyl moiety into complex organic structures. This is crucial for the synthesis of pharmaceuticals and agrochemicals.
Organic Synthesis Intermediate
Serves as a versatile intermediate for constructing intricate molecules. The pinacol ester form provides enhanced stability and handling compared to the free boronic acid.
Material Science Research
The trifluoromethoxy substituent can impart desirable electronic or physical properties to novel materials. This compound can be incorporated into polymers or organic electronic components.
| Molecular weight | 288.07 |
|---|---|
| Empirical formula | C13H16BF3O3 |
| Assay | 97% |
| Melting point | 60-65 °C |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)phenylboronic acid pinacol ester used for?
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This compound is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions and as an intermediate in organic synthesis for creating complex molecules, including potential pharmaceuticals and advanced materials.
What are the CAS number and formula for 4-(Trifluoromethoxy)phenylboronic acid pinacol ester?
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The CAS number is 474709-28-9 and the molecular formula is C13H16BF3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
What are the safety and handling precautions for this chemical?
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This compound is classified as harmful if swallowed (H302) and carries a Warning signal word. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area, avoiding ingestion and contact with skin and eyes.
Can this chemical be shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-(Trifluoromethoxy)phenylboronic acid pinacol ester, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quotation or a sample of 4-(Trifluoromethoxy)phenylboronic acid pinacol ester.
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