4-(Trifluoromethoxy)phenylacetylene
4-(Trifluoromethoxy)phenylacetylene (CAS: 160542-02-9) is an organic compound with the formula C9H5F3O and a molecular weight of 186.13 g/mol. This terminal alkyne serves as a valuable building block in organic synthesis. Its unique trifluoromethoxyaryl structure makes it useful for introducing fluorinated moieties into more complex molecules, finding applications in pharmaceutical research and material science.
- IUPAC
- 4-Ethynyl-1-(trifluoromethoxy)benzene
- Synonyms
- 4-Ethynyl-1-(trifluoromethoxy)benzene
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. The terminal alkyne functionality allows for various coupling reactions, such as Sonogashira coupling, to form new carbon-carbon bonds.
Pharmaceutical Research
A building block for the development of novel pharmaceutical compounds. The trifluoromethoxy group can influence lipophilicity and metabolic stability of drug candidates.
Material Science
Employed in the creation of new materials, particularly where fluorinated aromatic structures are desired for specific electronic or physical properties.
| Molecular weight | 186.13 |
|---|---|
| Empirical formula | C9H5F3O |
| Assay | 97% |
| Density | 1.215 g/mL at 25 °C |
| Refractive index | n20/D 1.4554 |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 40 °C / 104 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36-43-51/53 |
| Safety statements (S) | 26-36/37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethoxy)phenylacetylene used for?
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4-(Trifluoromethoxy)phenylacetylene is primarily used as an intermediate and building block in organic synthesis, with applications in pharmaceutical research and material science.
What are the CAS number and formula for 4-(Trifluoromethoxy)phenylacetylene?
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The CAS number is 160542-02-9 and the chemical formula is C9H5F3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethoxy)phenylacetylene with an assay of 97%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 4-(Trifluoromethoxy)phenylacetylene be handled safely?
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4-(Trifluoromethoxy)phenylacetylene is a flammable liquid and vapour (H226) and is harmful if swallowed (H302). It may cause an allergic skin reaction (H317) and serious eye irritation (H319). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used. Handle in a well-ventilated area away from ignition sources.
How is this chemical exported by Tech Serve Solutions?
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Tech Serve Solutions is a global supplier and exporter of chemicals, adhering to all necessary regulations for international shipping, including UN 1993 classification for transport.
How can I request a sample or quote for 4-(Trifluoromethoxy)phenylacetylene?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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