Sivelestat sodium salt hydrate
Sivelestat sodium salt hydrate, CAS 127373-66-4 (free acid), is a white to off-white solid with the empirical formula C20H22N2O7S · xNa+ · yH2O. This compound functions primarily to inhibit human neutrophil elastase-mediated cell signalling. It is soluble in water and commonly employed in research settings within cell biology, cell signalling, and neuroscience, focusing on cytoskeletal dynamics and microtubule inhibition.
- IUPAC
- EI 546 sodium salt hydrate,Elaspol sodium salt hydrate,LY 544349 sodium salt hydrate,Ono-5046 sodium salt hydrate,o-(p-Hydroxybenzenesulfonamido)hippuric acid, pivalate (ester) sodium salt hydrate
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Inhibition of Neutrophil Elastase
Sivelestat sodium salt hydrate is utilised to investigate and inhibit the cell signalling pathways mediated by human neutrophil elastase. This action is relevant in understanding inflammatory responses and associated cellular processes.
Cell Biology Research
As a tool in cell biology, this compound aids in studying cellular functions, particularly those involving cell signalling and the cytoskeleton. Its properties make it valuable for examining microtubule dynamics and extracellular matrix interactions.
Neuroscience Studies
The compound finds application in neuroscience research, particularly in areas related to cell signalling mechanisms that impact neural cells. It helps researchers explore the intricate pathways involved in neuronal function and response.
| Empirical formula | C20H22N2O7S · xNa+ · yH2O |
|---|---|
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: >20 mg/mL |
| Storage temperature | room temp |
| Application | Sivelestat sodium salt hydrate may be used to inhibit human neutrophil elastase-mediated cell signaling. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | nwg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sivelestat sodium salt hydrate used for?
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Sivelestat sodium salt hydrate is primarily used to inhibit human neutrophil elastase-mediated cell signalling, making it a valuable tool in cell biology, cell signalling, neuroscience, and cytoskeleton research.
What is the CAS number and formula for Sivelestat sodium salt hydrate?
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The CAS number for the free acid is 127373-66-4, and the empirical formula is C20H22N2O7S · xNa+ · yH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sivelestat sodium salt hydrate with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Sivelestat sodium salt hydrate?
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When handling Sivelestat sodium salt hydrate, it is recommended to use eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is advised. The compound is not classified as hazardous under German GHS (WGK nwg).
How is Sivelestat sodium salt hydrate packed, shipped, and exported?
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Sivelestat sodium salt hydrate is typically supplied as a white to off-white solid and stored at room temperature. We are a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for Sivelestat sodium salt hydrate?
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To request a sample or quote, please contact our sales team through the website or by telephone. We will be happy to assist you with your specific requirements.
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