Simvastatin

CAS 79902-63-9C25H38O5Cell Biology

Simvastatin (CAS: 79902-63-9, C25H38O5) is a white, solid organic compound with a molecular weight of 418.57 g/mol. It is a widely researched molecule with applications in studying cellular transport mechanisms and the effects of endothelial dysfunction. Simvastatin is primarily utilized in biochemical and pharmacological research to investigate pathways related to lipid metabolism and cellular signalling.

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Simvastatin (C25H38O5) — chemical structure, CAS 79902-63-9; Life Science, fine chemical supplied by Tech Serve Solutions

Arachidonic Acid CascadeBioactive Small MoleculesCancer MetabolismCancer ResearchCell BiologyEnzyme InhibitorsLipids in Cell SignalingMerckMevalonate Pathway in CancerOther

01 /Applications

Cellular Transport Studies

Simvastatin has been employed in research to examine the role of specific transporter proteins, such as ATP-binding cassette transporter A7, in cellular processes like phagocytosis.

Endothelial Dysfunction Research

This compound has been used in studies involving animal models to investigate the impact of simvastatin on endothelial dysfunction and associated inflammatory responses.

Biochemical Research Tool

As a well-characterized molecule, Simvastatin serves as a valuable tool in biochemical research, particularly for investigating lipid metabolism and related cellular signalling pathways.

02 /Properties

Molecular weight	418.57
Empirical formula	C25H38O5
Assay	≥97% (HPLC)
Form	solid
Colour	white
Solubility	DMSO: ≥20 mg/mL
Storage temperature	2-8°C
Melting point	127-132 °C(lit.)
Application	Simvastatin was used to study the role of ATP-binding cassette transporter A7 in phagocytosis of Jurkat cells.3 Mice were treated with simvastatin to study the effect on endothelial dysfunction and inflammation.4

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

79902-63-9

MDL number

MFCD00072007

05 /Additional specifications

Gene Information	human ... HMGCR(3156)rat ... Hmgcr(25675)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Simvastatin used for?

Simvastatin is used in research to study cellular transport mechanisms, endothelial dysfunction, and lipid metabolism pathways. It is not for human or veterinary use.

What is the CAS number and chemical formula for Simvastatin?

The CAS number for Simvastatin is 79902-63-9, and its chemical formula is C25H38O5.

What grade and purity does Tech Serve Solutions supply for Simvastatin?

Tech Serve Solutions supplies Simvastatin with a minimum purity of 97% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the safety precautions for handling Simvastatin?

When handling Simvastatin, it is recommended to use eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Ensure adequate ventilation.

How is Simvastatin shipped and exported?

Simvastatin is typically stored at 2-8°C. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping regulations.