Sodium (R)-β-hydroxyisobutyrate
Sodium (R)-β-hydroxyisobutyrate (CAS: 1228078-57-6), with the molecular formula C4H7NaO3 and a molecular weight of 126.09 g/mol, is a chiral organic compound. It is utilised in biochemical research, particularly in the study of metabolic pathways and cell biology. This sodium salt plays a role in investigations concerning gluconeogenesis and metabolomics, providing a stereospecific option for enzymatic studies.
- IUPAC
- (R)-β-Hydroxyisobutyric acid sodium salt,(R)-3-Hydroxy-2-methylpropionic acid sodium salt,R-HIBA,Sodium (R)-3-hydroxy-2-methylpropionate
- Synonyms
- (R)-β-Hydroxyisobutyric acid sodium salt(R)-3-Hydroxy-2-methylpropionic acid sodium saltR-HIBASodium (R)-3-hydroxy-2-methylpropionate
Enzyme Activity Studies
Sodium (R)-β-hydroxyisobutyrate can be employed to investigate the kinetics and distribution of enzymes involved in branched-chain amino acid metabolism. It is particularly useful for studying enzymes like 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31).
Stereospecific Biochemical Research
The compound's specific (R)-configuration makes it suitable for stereospecific studies within metabolic pathways. This allows researchers to differentiate between enantiomers in biochemical reactions and metabolic profiling.
Metabolomics and Cell Biology Research
As a component of metabolic pathways, Sodium (R)-β-hydroxyisobutyrate is relevant in metabolomics studies. It can also be used in cell biology research to understand cellular metabolic processes and their regulation.
| Molecular weight | 126.09 |
|---|---|
| Empirical formula | C4H7NaO3 |
| Assay | ≥96.0% (GC)≥96.0% |
| Optical purity | enantiomeric excess: ≥98.0% |
| Storage temperature | 2-8°C |
| Application | 3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). (R)-β-hydroxyisobutyrate may be used in stereospecific studies. |
| Composition | sodium, 17.5-19.0% |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium (R)-β-hydroxyisobutyrate used for?
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Sodium (R)-β-hydroxyisobutyrate is primarily used in biochemical research for studying metabolic pathways, cell biology, gluconeogenesis, and metabolomics. It is particularly useful for investigating enzyme kinetics, such as those involving 3-hydroxyisobutyrate dehydrogenase, and for stereospecific studies due to its defined (R)-configuration.
What is the CAS number and formula for Sodium (R)-β-hydroxyisobutyrate?
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The CAS number for Sodium (R)-β-hydroxyisobutyrate is 1228078-57-6, and its molecular formula is C4H7NaO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium (R)-β-hydroxyisobutyrate with an assay of ≥96.0% (GC) and an enantiomeric excess of ≥98.0%. This product is supplied for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Sodium (R)-β-hydroxyisobutyrate be stored?
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Sodium (R)-β-hydroxyisobutyrate should be stored under refrigeration at 2-8°C.
What are the hazards associated with Sodium (R)-β-hydroxyisobutyrate?
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According to the Globally Harmonised System (GHS), Sodium (R)-β-hydroxyisobutyrate has a WGK Germany classification of 3, indicating it is hazardous to water. Appropriate handling procedures should be followed to avoid environmental release.
How can I request a quote or sample?
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To request a quote or sample of Sodium (R)-β-hydroxyisobutyrate, please contact our sales team through the website or via email, providing your specific requirements.
Does TSS export Sodium (R)-β-hydroxyisobutyrate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Sodium (R)-β-hydroxyisobutyrate.
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