Sodium phenylbutyrate
Sodium phenylbutyrate (CAS: 1716-12-7; Formula: C10H11NaO2; MW: 186.18 g/mol) is a white to beige powder with good solubility in water. As a derivative of butyric acid, it functions as a histone deacetylase (HDAC) inhibitor. Its applications span cell biology research, focusing on gene regulation and cell signalling, particularly in neuroscience. It is supplied by TSS for research and development purposes.
- IUPAC
- 4-PBA,4-Phenylbutyric acid,4-phenylbutyrate,Buphenyl,Sodium 4-phenylbutyrate,TriButyrate
- Synonyms
- 4-PBA4-Phenylbutyric acid4-phenylbutyrateBuphenylSodium 4-phenylbutyrateTriButyrate
Histone Deacetylase (HDAC) Inhibition
Sodium phenylbutyrate acts as a chemical chaperone and HDAC inhibitor. It is used in research to modulate gene expression and epigenetic modifications, influencing cellular processes.
Cellular Differentiation Studies
This compound is employed in studies investigating cellular differentiation and development. Its ability to alter gene expression patterns makes it a valuable tool in understanding cell fate.
Neuroscience Research
In neuroscience, sodium phenylbutyrate is utilised to explore pathways related to neuroprotection and the modulation of neuronal function. It aids in the investigation of neurological disorders at a cellular level.
Gene Regulation and Expression Research
Researchers use sodium phenylbutyrate to study DNA-RNA transcription and gene regulation. It provides a means to influence the accessibility of DNA and the activity of transcription factors.
| Molecular weight | 186.18 |
|---|---|
| Empirical formula | C10H11NaO2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: ≥5 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium phenylbutyrate used for?
+
Sodium phenylbutyrate is primarily used in research for its properties as a histone deacetylase (HDAC) inhibitor and chemical chaperone. It is employed in studies related to cell biology, gene regulation, cell signalling, neuroscience, and cellular differentiation.
What is the CAS number and formula for Sodium phenylbutyrate?
+
The CAS number for Sodium phenylbutyrate is 1716-12-7, and its molecular formula is C10H11NaO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Sodium phenylbutyrate with an assay of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Sodium phenylbutyrate be handled and stored?
+
Sodium phenylbutyrate is classified as a Warning substance (GHS07) and can cause serious eye irritation (H319). Handle with appropriate personal protective equipment, especially eye protection. Store at room temperature.
Is Sodium phenylbutyrate a controlled substance?
+
The provided data does not indicate that Sodium phenylbutyrate is a controlled substance.
How can I request a sample or quote for Sodium phenylbutyrate?
+
To request a sample or a quote for Sodium phenylbutyrate, please contact the TSS sales department through our website or direct inquiry channels.
How is Sodium phenylbutyrate packed and shipped?
+
Sodium phenylbutyrate is typically supplied as a powder. Specific packaging and shipping details for export orders are handled according to international regulations and customer requirements.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis