4-Fluorobenzylamine
4-Fluorobenzylamine (CAS: 140-75-0; Formula: FC6H4CH2NH2; MW: 125.14) is a key organic intermediate and building block. Characterized by its fluorinated phenyl ring and primary amine group, it serves as a valuable reagent in chemical synthesis. Its primary application lies in the preparation of complex molecules, notably in the field of coordination chemistry and the development of novel chelates, contributing to advanced material and pharmaceutical research.

Synthesis of Tris-Iron(III) Chelates
4-Fluorobenzylamine has been utilized in the synthesis of novel tris-iron(III) chelates. These chelates are derived from 3-hydroxy-4-pyridinone ligands, demonstrating its utility in coordination chemistry and the development of metal-binding agents.
Organic Synthesis Building Block
As a fluorinated aryl building block, 4-Fluorobenzylamine is instrumental in introducing the 4-fluorobenzyl moiety into organic molecules. This makes it valuable for constructing complex structures in pharmaceutical and agrochemical research.
Research and Development
This compound serves as a versatile reagent in academic and industrial research laboratories. Its specific structure allows for diverse chemical transformations, aiding in the exploration of new chemical entities and reaction pathways.
| Molecular weight | 125.14 |
|---|---|
| Linear formula | FC6H4CH2NH2 |
| Assay | 97% |
| Boiling point | 183 °C(lit.) |
| Density | 1.095 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.512(lit.) |
| Application | 4-Fluorobenzylamine was used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands1. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... AOC3(8639)mouse ... Aoc3(11754) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzylamine used for?
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4-Fluorobenzylamine is used as a building block in organic synthesis, particularly for creating fluorinated compounds and in the preparation of metal chelates, such as tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands.
What is the CAS number and chemical formula for 4-Fluorobenzylamine?
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The CAS number for 4-Fluorobenzylamine is 140-75-0, and its chemical formula is FC6H4CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorobenzylamine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Fluorobenzylamine be handled safely?
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4-Fluorobenzylamine is a Danger hazard (GHS05, H314), causing severe skin burns and eye damage. Handle with extreme care using appropriate personal protective equipment, including gloves, goggles, a full-face shield, and a suitable respirator. Ensure adequate ventilation.
Is 4-Fluorobenzylamine a controlled substance?
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The provided data does not indicate that 4-Fluorobenzylamine is a controlled substance.
How is 4-Fluorobenzylamine packed, shipped, and exported?
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4-Fluorobenzylamine is classified under UN 2735, AMINES, LIQUID, CORROSIVE, N.O.S. (or 3-Fluorobenzylamine), PG II. Tech Serve Solutions adheres to all regulations for safe packing, shipping, and global export of this chemical.
How can I request a sample or quote for 4-Fluorobenzylamine?
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To request a sample or obtain a quote for 4-Fluorobenzylamine, please contact our sales team through the website or by phone.
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