4-Fluorobenzyl chloride
4-Fluorobenzyl chloride (CAS: 352-11-4), with the molecular formula FC6H4CH2Cl and a molecular weight of 144.57 g/mol, is a halogenated organic compound. This chemical serves as a valuable building block in organic synthesis, particularly for introducing the 4-fluorobenzyl moiety into target molecules. It is frequently employed in the development of pharmaceuticals, agrochemicals, and advanced materials.
- IUPAC
- α-Chloro-4-fluorotoluene,1-Chloromethyl-4-fluorobenzene
- Synonyms
- α-Chloro-4-fluorotoluene1-Chloromethyl-4-fluorobenzene
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the 4-fluorobenzyl group is a key structural component. Its reactivity allows for the construction of complex drug molecules.
Agrochemical Synthesis
Serves as a precursor in the production of various pesticides and herbicides. The introduction of fluorine can often enhance the biological activity and stability of agrochemical products.
Organic Building Block
A versatile reagent in general organic chemistry for creating new carbon-carbon or carbon-heteroatom bonds. It is especially useful for reactions involving benzyl halides.
Materials Science
Can be incorporated into the synthesis of specialty polymers or functional materials. The presence of fluorine can impart unique properties such as thermal stability or altered electronic characteristics.
| Molecular weight | 144.57 |
|---|---|
| Linear formula | FC6H4CH2Cl |
| Assay | 99% |
| Boiling point | 82 °C/26 mmHg(lit.) |
| Density | 1.207 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.513(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzyl chloride used for?
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4-Fluorobenzyl chloride is primarily used as an intermediate and building block in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. It is valuable for introducing the 4-fluorobenzyl group into various organic molecules.
What are the CAS number and molecular formula for 4-Fluorobenzyl chloride?
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The CAS number for 4-Fluorobenzyl chloride is 352-11-4, and its molecular formula is FC6H4CH2Cl.
What grade and purity does Tech Serve Solutions supply for 4-Fluorobenzyl chloride?
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Tech Serve Solutions supplies 4-Fluorobenzyl chloride with an assay of 99%. This product is supplied for research and development or technical purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-Fluorobenzyl chloride be handled safely?
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4-Fluorobenzyl chloride is a Danger material (H314 - Causes severe skin burns and eye damage). Handle with extreme caution using appropriate personal protective equipment, including gloves, goggles, a faceshield, and a suitable respirator. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing.
How is 4-Fluorobenzyl chloride packed, shipped, and exported?
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Tech Serve Solutions, a specialist global supplier, packs and exports 4-Fluorobenzyl chloride in compliance with international shipping regulations for hazardous materials (UN 2920, Class 3(8), PG II). Specific packaging will be detailed on your quotation.
How can I request a sample or quote for 4-Fluorobenzyl chloride?
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To request a sample or obtain a quotation for 4-Fluorobenzyl chloride, please contact our sales department via the website or by calling our dedicated line. Our team will assist you promptly.
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