6-Hydroxypyridine-3-carboxylic acid
6-Hydroxypyridine-3-carboxylic acid (CAS 5006-66-6), with the molecular formula C6H5NO3 and a molecular weight of 139.11 g/mol, is a heterocyclic compound. It serves as a valuable building block in chemical synthesis. Its primary documented application is in the preparation of molecularly imprinted polymers (MIPs), contributing to advancements in materials science and separation technologies.
- IUPAC
- 2-Hydroxy-5-pyridinecarboxylic acid,6-Hydroxynicotinic acid

Synthesis of Molecularly Imprinted Polymers (MIPs)
6-Hydroxypyridine-3-carboxylic acid has been utilised in the creation of molecularly imprinted polymers. MIPs are synthetic materials designed with specific recognition sites for target molecules, finding applications in sensing, drug delivery, and chromatography.
Heterocyclic Building Block
As a pyridine derivative, this compound functions as a versatile building block in organic synthesis. Its functional groups allow for diverse chemical modifications and incorporation into more complex molecular structures.
Chemical Synthesis Intermediate
This chemical is employed as an intermediate in various chemical synthesis pathways. Its structure lends itself to the development of novel compounds for research and development purposes across different scientific disciplines.
| Molecular weight | 139.11 |
|---|---|
| Empirical formula | C6H5NO3 |
| Assay | ≥98.0% (HPLC) |
| Application | 6-Hydroxypyridine-3-carboxylic acid (6-Hydroxynicotinic acid) was used in the synthesis of molecularly imprinted polymer (MIP)1. |
| Melting point | >300 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Hydroxypyridine-3-carboxylic acid used for?
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6-Hydroxypyridine-3-carboxylic acid is primarily used as a building block in chemical synthesis, notably in the preparation of molecularly imprinted polymers (MIPs).
What are the CAS number and formula for 6-Hydroxypyridine-3-carboxylic acid?
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The CAS number is 5006-66-6, and the molecular formula is C6H5NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Hydroxypyridine-3-carboxylic acid with a purity of ≥98.0% (HPLC). We do not represent this product as meeting USP, BP, EP, or other pharmacopoeia standards.
How should 6-Hydroxypyridine-3-carboxylic acid be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. It may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Ensure adequate ventilation and avoid dust formation.
Can this chemical be packed and exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can provide this product for your requirements.
How can I request a sample or quote for 6-Hydroxypyridine-3-carboxylic acid?
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To request a sample or obtain a quote, please contact our sales team through the website or by phone, referencing the product name and CAS number 5006-66-6.
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