6-Hydroxypyridine-3-boronic acid pinacol ester
6-Hydroxypyridine-3-boronic acid pinacol ester (CAS: 1054483-78-1, Formula: C11H16BNO3) is a valuable organoboron compound with a molecular weight of 221.06 g/mol. This heteroaryl boronate ester serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions. Its pyridine and boronate ester functionalities make it an important intermediate for the development of complex molecules in pharmaceutical research and material science.
- IUPAC
- 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine,2-Hydroxypyridine-5-boronic acid, pinacol ester
- Synonyms
- 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine2-Hydroxypyridine-5-boronic acid, pinacol ester
Suzuki-Miyaura Cross-Coupling Reactions
This compound is extensively used as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds by reacting with aryl or vinyl halides, enabling the synthesis of biaryl compounds and substituted pyridines.
Medicinal Chemistry
It serves as a key intermediate in the synthesis of novel pharmaceutical agents. The pyridine core and the boronate ester group allow for diverse structural modifications, leading to potential drug candidates.
Material Science
The unique structural features of 6-Hydroxypyridine-3-boronic acid pinacol ester make it useful in the development of new organic materials with specific electronic or optical properties.
Organic Synthesis Intermediate
As a functionalized boronate ester, it is a crucial reagent for constructing complex organic frameworks in various research and development settings.
| Molecular weight | 221.06 |
|---|---|
| Empirical formula | C11H16BNO3 |
| Assay | 97% |
| Melting point | 196-200 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Hydroxypyridine-3-boronic acid pinacol ester used for?
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6-Hydroxypyridine-3-boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the creation of carbon-carbon bonds, and in the development of new molecules for medicinal chemistry and material science.
What are the CAS number and formula for 6-Hydroxypyridine-3-boronic acid pinacol ester?
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The CAS number is 1054483-78-1, and the empirical formula is C11H16BNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Hydroxypyridine-3-boronic acid pinacol ester with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with this compound?
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This compound is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315) and serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used when handling it. Ensure good ventilation.
How is 6-Hydroxypyridine-3-boronic acid pinacol ester shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ships and exports chemicals worldwide, adhering to all relevant regulations for safe and compliant transport.
How can I request a sample or obtain a quote?
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To request a sample or a quotation for 6-Hydroxypyridine-3-boronic acid pinacol ester, please contact our sales team through the website or via direct inquiry.
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