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Sodium (S)-β-hydroxyisobutyrate

CAS 26543-05-5 (free acid)C4H7NaO3Cell Biology

Sodium (S)-β-hydroxyisobutyrate (CAS: 26543-05-5, C4H7NaO3) is a chemical compound with a molecular weight of 126.09 g/mol. It is specifically the sodium salt of (S)-3-hydroxyisobutyric acid. This enantiomerically pure compound is valuable in biochemical research, particularly for studying metabolic pathways and enzyme kinetics within cell biology and gluconeogenesis.

IUPAC
(S)-β-Hydroxy-isobutyric acid sodium salt,(S)-3-Hydroxy-2-methylpropionic acid sodium salt,S-HIBA,Sodium (S)-3-hydroxy-2-methylpropionate
Synonyms
(S)-β-Hydroxy-isobutyric acid sodium salt(S)-3-Hydroxy-2-methylpropionic acid sodium saltS-HIBASodium (S)-3-hydroxy-2-methylpropionate
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Sodium (S)-β-hydroxyisobutyrate (C4H7NaO3) — chemical structure, CAS 26543-05-5 (free acid); Life Science, fine chemical supplied by Tech Serve Solutions
Cell BiologyGluconeogenesisMetabolic PathwaysMetabolomics
01 /Applications

Biochemical Research

Utilised in the study of enzymes involved in branched-chain amino acid metabolism, such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31).

Stereospecific Studies

Serves as a substrate in investigations requiring stereochemically defined molecules, particularly in the context of (S)-β-hydroxyisobutyrate metabolism.

Metabolic Pathway Analysis

Employed in metabolomics and the characterisation of metabolic pathways, including gluconeogenesis, to understand cellular energy and substrate flow.

02 /Properties
Molecular weight126.09
Empirical formulaC4H7NaO3
Assay≥96.0% (GC)≥96.0%
Optical purityenantiomeric excess: ≥98.0%
Storage temperature2-8°C
Application3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). (S)-β-hydroxyisobutyrate may be used in stereospecific studies.
Compositionsodium, 17.5-19.0%
03 /Identifiers & registry
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Sodium (S)-β-hydroxyisobutyrate used for?

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It is used in biochemical research to study enzymes involved in branched-chain amino acid metabolism and in stereospecific studies related to metabolic pathways and cell biology.

What is the CAS number and formula for Sodium (S)-β-hydroxyisobutyrate?

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The CAS number is 26543-05-5 (for the free acid) and the empirical formula is C4H7NaO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Sodium (S)-β-hydroxyisobutyrate with an assay of ≥96.0% (GC) and an enantiomeric excess of ≥98.0%. TSS does not represent this product as USP, BP, or EP grade.

What are the safety and handling recommendations for this product?

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This compound has a WGK (Germany) classification of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment and follow standard laboratory safety procedures.

How is Sodium (S)-β-hydroxyisobutyrate packed, shipped, and exported?

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Tech Serve Solutions packs, ships, and exports fine chemicals globally, adhering to all relevant regulations for safe and compliant transport.

How can I request a quote or sample for Sodium (S)-β-hydroxyisobutyrate?

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Please contact our sales team via the website or phone to request a quote or sample. We are happy to assist with your research needs.

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