Sitaxentan sodium salt

CAS 210421-74-2C18H14ClN2NaO6S2Cell Biology

Sitaxentan sodium salt (CAS: 210421-74-2), with the empirical formula C18H14ClN2NaO6S2, is a white to beige powder. This selective endothelin receptor antagonist plays a crucial role in cell biology research, particularly in studies involving cell signaling and neuroscience. It is recognised for its application in investigating the endothelin pathway and its downstream effects, offering a valuable tool for researchers in these fields.

IUPAC: N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide sodium salt,Sitaxsentan sodium salt,TBC-11251 sodium salt,Thelin
Synonyms: N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide sodium saltSitaxsentan sodium saltTBC-11251 sodium saltThelin

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Sitaxentan sodium salt (C18H14ClN2NaO6S2) — chemical structure, CAS 210421-74-2; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsCell BiologyEndothelinsPeptides and Proteins

01 /Applications

Endothelin Receptor Antagonism Research

Sitaxentan sodium salt serves as a potent and selective antagonist of the endothelin ET(A) receptor. It is widely utilised in biochemical and cellular assays to elucidate the physiological and pathological roles of endothelin signalling.

Cell Signaling Pathway Studies

This compound is instrumental in researching cell signaling cascades regulated by endothelin, a key mediator in cardiovascular and pulmonary functions. Its use aids in understanding complex biological processes at a molecular level.

Neuroscience Research Tool

Within neuroscience, Sitaxentan sodium salt is employed to investigate the impact of endothelin on neuronal function and dysfunction. This contributes to a deeper understanding of neurological disorders and potential therapeutic targets.

02 /Properties

Empirical formula	C18H14ClN2NaO6S2
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	H2O: soluble10 mg/mL (clear solution)
Storage temperature	room temp

03 /Identifiers & registry

CAS number

210421-74-2

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Sitaxentan sodium salt used for?

Sitaxentan sodium salt is used as a selective endothelin ET(A) receptor antagonist in cell biology research, particularly in studies of cell signaling, neuroscience, and the endothelin pathway.

What is the CAS number and formula for Sitaxentan sodium salt?

The CAS number for Sitaxentan sodium salt is 210421-74-2, and its empirical formula is C18H14ClN2NaO6S2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Sitaxentan sodium salt with a purity of ≥98% as determined by HPLC. This product is intended for research and laboratory use. We do not represent it as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling considerations for Sitaxentan sodium salt?

Sitaxentan sodium salt is classified with a WGK Germany of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding dust formation and release into the environment.

How is Sitaxentan sodium salt packed and shipped?

Sitaxentan sodium salt is supplied as a white to beige powder and is stored at room temperature. We are experienced in exporting fine chemicals globally.

How can I request a sample or quote for Sitaxentan sodium salt?

To request a sample or a quotation for Sitaxentan sodium salt, please contact our sales team via the website or direct email, providing your specific requirements and delivery details.