Silibinin
Silibinin (CAS: 22888-70-6), with the molecular formula C25H22O10, is a naturally occurring flavonoid isolated from milk thistle. Known for its antioxidant and anti-inflammatory properties, Silibinin is extensively researched for its potential therapeutic applications, particularly in areas of cancer research and liver protection. It serves as a valuable phytochemical in cell biology and nutrition research, with ongoing studies exploring its role as a chemopreventive agent.
- IUPAC
- 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin,Silybin
- Synonyms
- Silybin

Cancer Research
Silibinin is investigated for its antiproliferative and pro-apoptotic effects in various cancer cell lines. Its role in inhibiting angiogenesis and modulating cellular signalling pathways makes it a subject of interest in oncology research.
Hepatoprotective Agent
Due to its antioxidant properties, Silibinin is studied for its protective effects against liver damage caused by toxins and certain medications. It aids in the regeneration of liver cells and reduces oxidative stress.
Cell Biology Studies
As a natural compound with diverse biological activities, Silibinin is utilized in cell biology research to understand gene regulation, cell signalling, and inflammatory responses.
Nutrition Research
Silibinin's presence in dietary supplements and its health benefits are explored in nutrition research, particularly concerning its antioxidant capacity and potential contributions to overall wellness.
| Molecular weight | 482.44 |
|---|---|
| Empirical formula | C25H22O10 |
| Assay | ≥98% (HPLC) |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Silibinin used for?
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Silibinin is primarily used in research settings for its potential applications in cancer research, as a hepatoprotective agent, in cell biology studies, and in nutrition research due to its antioxidant and anti-inflammatory properties.
What is the CAS number and formula for Silibinin?
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Silibinin has the CAS number 22888-70-6 and the molecular formula C25H22O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Silibinin with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Silibinin be handled and stored?
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Silibinin is classified as an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves. Store at −20°C.
Is Silibinin a controlled substance?
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The provided data does not indicate that Silibinin (CAS: 22888-70-6) is a controlled substance.
How is Silibinin packed, shipped, and exported?
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Silibinin is carefully packed and prepared for global export by Tech Serve Solutions, adhering to international shipping regulations for fine chemicals.
How can I request a sample or quote for Silibinin?
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To request a sample or a quote for Silibinin, please contact our sales team through the website or by phone.
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