4-Acetoxy-2-azetidinone
4-Acetoxy-2-azetidinone (CAS 28562-53-0), with the molecular formula C5H7NO3 and a molecular weight of 129.11 g/mol, is a versatile organic building block. It functions as a key heterocyclic synthon, particularly valuable in the synthesis of complex molecules. Its applications span the creation of derivatized cyclopentenes with precise stereochemical control, contributing to the development of novel antibiotic and anti-inflammatory agents.

Synthesis of Derivatized Cyclopentenes
4-Acetoxy-2-azetidinone has been utilised in synthetic routes to generate cyclopentene derivatives. These reactions proceed with high regio- and diastereoselectivity, offering precise control over molecular architecture.
Heterocyclic Synthon for Pharmaceuticals
As a valuable heterocyclic synthon, this compound plays a role in the development of biologically active molecules. It has been employed in the synthesis of potential antibiotic and anti-inflammatory drug candidates.
Organic Synthesis Building Block
This azetidinone derivative serves as a fundamental building block in various organic synthesis pathways. Its reactive nature allows for diverse chemical transformations, facilitating the construction of complex organic structures.
| Molecular weight | 129.11 |
|---|---|
| Empirical formula | C5H7NO3 |
| Assay | 98% |
| Solubility | formic acid: soluble50 mg/mL, clear, yellow-orange |
| Storage temperature | 2-8°C |
| Application | 4-Acetoxy-2-azetidinone was used in the synthesis of derivatized cyclopentenes in high regio- and diastereoselectivity1. It was also used as a heterocyclic synthon2 for antibiotic3 and anti-inflammatory4 agents. |
| Melting point | 38-40 °C(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 1759 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Acetoxy-2-azetidinone used for?
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4-Acetoxy-2-azetidinone is used as a heterocyclic synthon in organic synthesis, notably in the preparation of derivatized cyclopentenes with high regio- and diastereoselectivity, and in the synthesis of antibiotic and anti-inflammatory agents.
What are the CAS number and formula for 4-Acetoxy-2-azetidinone?
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The CAS number for 4-Acetoxy-2-azetidinone is 28562-53-0, and its empirical formula is C5H7NO3.
What grade and purity does Tech Serve Solutions supply for 4-Acetoxy-2-azetidinone?
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Tech Serve Solutions supplies 4-Acetoxy-2-azetidinone with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
What are the primary safety concerns when handling 4-Acetoxy-2-azetidinone?
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4-Acetoxy-2-azetidinone is classified as Danger, with hazards including severe skin burns and eye damage (H314) and a risk of causing allergy or asthma symptoms or breathing difficulties if inhaled (H334). Appropriate personal protective equipment, including eyeshields, face shields, and respiratory protection, is essential.
How is 4-Acetoxy-2-azetidinone typically stored and shipped?
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4-Acetoxy-2-azetidinone is typically stored at 2-8°C. It is shipped internationally by Tech Serve Solutions as a fine chemical suitable for laboratory and research applications.
How can I request a quote or sample for 4-Acetoxy-2-azetidinone?
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To request a quote or a sample of 4-Acetoxy-2-azetidinone, please contact our sales team via the website or by phone. Our representatives will be pleased to assist you with your inquiry.
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