4-Acetamidothiophenol
4-Acetamidothiophenol (CAS: 1126-81-4) is a valuable organic building block for chemical synthesis. With a molecular weight of 167.23 g/mol, this thiol compound offers a reactive sulfur atom and an acetamide group, enabling diverse chemical transformations. It is typically supplied at an assay of 95% and requires storage at 2-8°C. This compound serves as a key intermediate in the development of more complex molecules within research and industrial settings.
- IUPAC
- 4′-Mercaptoacetanilide
- Synonyms
- 4-Mercaptoacetanilidep-AcetamidothiophenolN-(4-mercaptophenyl)acetamide

Organic Synthesis Intermediate
4-Acetamidothiophenol is a versatile building block used in the synthesis of various organic compounds. Its functional groups allow for participation in a range of reactions, making it useful for creating more complex molecular structures.
Pharmaceutical Research
This compound can serve as a precursor or intermediate in the development of novel pharmaceutical agents. Its structure lends itself to modifications for targeted drug discovery programmes.
Materials Science
The thiol group in 4-Acetamidothiophenol can be utilised in the development of functional materials, potentially for surface modification or polymer synthesis.
| Molecular weight | 167.23 |
|---|---|
| Linear formula | CH3CONHC6H4SH |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 150-153 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Acetamidothiophenol used for?
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4-Acetamidothiophenol is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and materials science, due to its reactive thiol and acetamide functionalities.
What are the CAS number and chemical formula for 4-Acetamidothiophenol?
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The CAS number for 4-Acetamidothiophenol is 1126-81-4. Its linear formula is CH3CONHC6H4SH.
What grade and purity does Tech Serve Solutions supply for 4-Acetamidothiophenol?
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Tech Serve Solutions supplies 4-Acetamidothiophenol with an assay of 95%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 4-Acetamidothiophenol be handled safely?
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Due to its irritant properties (H315, H319, H335), handling 4-Acetamidothiophenol requires appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Ensure good ventilation and avoid dust formation.
How is 4-Acetamidothiophenol packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports chemicals globally, adhering to all relevant regulations to ensure safe and timely delivery.
How can I request a sample or quote for 4-Acetamidothiophenol?
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To request a sample or a quote for 4-Acetamidothiophenol, please contact our sales team through the website or by phone, providing your specific requirements.
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