L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride (CAS: 6234-01-1) is a specialised derivative of glutamic acid. This compound features esterification at both the alpha-carboxyl group (as a methyl ester) and the gamma-carboxyl group (as a tert-butyl ester), presented as its hydrochloride salt. It serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and amino acid derivative research.
Peptide Synthesis
This ester derivative of glutamic acid is employed as a protected amino acid in solid-phase or solution-phase peptide synthesis. The tert-butyl and methyl ester groups offer orthogonal protection strategies, allowing for selective deprotection during complex peptide chain assembly.
Chemical Biology Research
As a modified amino acid, it can be used in studies investigating protein structure, function, or the development of novel biochemical probes. Its specific esterification pattern may influence its interactions or reactivity in biological systems.
Organic Synthesis Intermediate
The compound acts as a versatile intermediate for the synthesis of various organic molecules. Its functional groups (ester, amine hydrochloride) can be selectively modified to create more complex structures for diverse chemical applications.
| Molecular weight | 253.72 |
|---|---|
| Linear formula | (CH3)3COOCCH2CH2CH(NH2)COOCH3 |
| Assay | ≥95.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride used for?
+
L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride is primarily used as a protected amino acid building block in peptide synthesis and as an intermediate in general organic synthesis and chemical biology research.
What are the CAS number and molecular formula?
+
The CAS number is 6234-01-1. The linear formula is (CH3)3COOCCH2CH2CH(NH2)COOCH3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride with an assay of ≥95.0% (determined by TLC). This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions?
+
This compound requires the use of safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended for respiratory protection. It is classified with WGK 3 in Germany, indicating a significant hazard to water.
How is this chemical stored and shipped?
+
This chemical should be stored at 2-8°C. Tech Serve Solutions ensures that all products are packaged and exported in compliance with international shipping regulations for chemicals.
How can I request a quote or sample?
+
To request a quote or a sample of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride, please visit the Tech Serve Solutions website or contact our sales department directly.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis