H-Lys(Boc)-OH

CAS 2418-95-3(CH3)3COCONH(CH2)4CH(NH2)COOHChemical Synthesis

Nε-Boc-L-lysine (CAS: 2418-95-3) is a protected amino acid derivative with a molecular weight of 246.30 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research. It serves as a crucial building block, allowing for controlled incorporation of lysine into peptide chains while preventing unwanted side reactions at the epsilon-amino group. Its availability from TSS supports advanced chemical synthesis and biochemical studies.

IUPAC: Nε-Boc-L-lysine
Synonyms: Nε-Boc-L-lysine

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H-Lys(Boc)-OH ((CH3)3COCONH(CH2)4CH(NH2)COOH) — chemical structure, CAS 2418-95-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisLysinePeptide Chemistry

01 /Applications

Peptide Synthesis

Nε-Boc-L-lysine is a fundamental reagent in solid-phase and solution-phase peptide synthesis. The Boc protecting group on the epsilon-amino function allows for selective deprotection and further functionalisation, enabling the construction of complex peptides with defined lysine side-chain modifications.

Chemical Biology

In chemical biology, this derivative is employed for modifying proteins and peptides to introduce labels, cross-linkers, or other functional groups. This facilitates studies into protein function, interactions, and cellular processes.

Organic Synthesis

As a versatile chiral building block, Nε-Boc-L-lysine finds application in various organic synthesis pathways beyond peptide chemistry. Its protected amino and carboxylic acid functionalities allow for diverse chemical transformations.

02 /Properties

Molecular weight	246.30
Linear formula	(CH3)3COCONH(CH2)4CH(NH2)COOH
Assay	≥97.0% (TLC)
Optical activity	[α]20/D +17±1°, c = 1% in acetic acid
Storage temperature	2-8°C
Melting point	250 °C (dec.)(lit.)~250 °C (dec.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2418-95-3

MDL number

MFCD00037221

PubChem substance

24862097

Beilstein registry

2417626

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Nε-Boc-L-lysine used for?

Nε-Boc-L-lysine is primarily used as a protected amino acid in peptide synthesis, chemical biology, and organic synthesis. The Boc group protects the epsilon-amino group of lysine.

What are the CAS number and formula for Nε-Boc-L-lysine?

The CAS number is 2418-95-3. The linear formula is (CH3)3COCONH(CH2)4CH(NH2)COOH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Nε-Boc-L-lysine with an assay of ≥97.0% (TLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should Nε-Boc-L-lysine be handled and stored?

Handle Nε-Boc-L-lysine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 or P1 respirator filter is recommended. Store at 2-8°C to maintain its stability and integrity. It has a melting point of approximately 250 °C with decomposition.

Is Nε-Boc-L-lysine a controlled substance?

The provided data does not indicate that Nε-Boc-L-lysine is a controlled substance.

How is this product packed and shipped?

Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details are available upon request, adhering to international regulations for chemical transport.