18-Crown-6
18-Crown-6 (CAS: 17455-13-9; Formula: C12H24O6; MW: 264.32 g/mol) is a cyclic polyether renowned for its ability to selectively bind alkali metal cations. This property makes it a highly effective complexing agent. Supplied by Tech Serve Solutions with a 'purum' grade, it is primarily utilised as a phase-transfer catalyst in organic synthesis and other chemical processes where cation complexation is required.
- IUPAC
- 1,4,7,10,13,16-Hexaoxacyclooctadecane,Hexaoxacyclooctadecane
- Synonyms
- 1,4,7,10,13,16-HexaoxacyclooctadecaneHexaoxacyclooctadecane
Phase-Transfer Catalysis
18-Crown-6 is widely employed as a phase-transfer catalyst in organic reactions. It facilitates the transfer of inorganic anions from an aqueous phase to an organic phase by complexing the accompanying metal cation, thereby increasing the solubility and reactivity of the anion in the organic solvent.
Ion Complexation
This crown ether exhibits a strong affinity for potassium ions (K+), due to the size of its central cavity. This selective complexation is fundamental to its use in various separation and purification processes involving potassium salts.
Chemical Synthesis Reagent
As a versatile synthetic reagent, 18-Crown-6 plays a crucial role in numerous chemical syntheses. Its ability to activate anions and modify reaction kinetics makes it invaluable for achieving desired transformations in complex molecular architectures.
| Molecular weight | 264.32 |
|---|---|
| Empirical formula | C12H24O6 |
| Grade | purum |
| Application | Can be useful as phase-transfer catalysts. |
| Melting point | 42-45 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 18-Crown-6 used for?
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18-Crown-6 is primarily used as a phase-transfer catalyst in organic synthesis and as a selective complexing agent for alkali metal cations, particularly potassium.
What is the CAS number and formula for 18-Crown-6?
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The CAS number for 18-Crown-6 is 17455-13-9, and its empirical formula is C12H24O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 18-Crown-6 with a 'purum' grade. We do not represent this product as pharmacopoeia grade (USP, BP, EP).
How should 18-Crown-6 be handled safely?
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Handle 18-Crown-6 with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes, as it is harmful if swallowed and causes skin, serious eye, and respiratory irritation (H302-H315-H319-H335).
How is 18-Crown-6 packed and shipped?
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18-Crown-6 is exported by Tech Serve Solutions following stringent international shipping regulations for chemicals. Specific packaging details are available upon request.
How can I request a sample or quote for 18-Crown-6?
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To request a sample or a quotation for 18-Crown-6, please contact our sales team through the website or via email, providing your specific requirements.
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