16-Mercaptohexadecanoic acid
16-Mercaptohexadecanoic acid (CAS: 69839-68-5), with the linear formula HS(CH2)15CO2H and a molecular weight of 288.49 g/mol, is a functional thiol building block. It is instrumental in materials science and micro/nanoelectronics for creating self-assembled monolayers (SAMs) on surfaces. Its carboxylic acid terminus allows for further functionalization, enabling the construction of complex multi-layered structures and hydrophilic surfaces for advanced applications.
- IUPAC
- MHDA

Self-Assembled Monolayers (SAMs)
16-Mercaptohexadecanoic acid is employed in the formation of SAMs on various substrates. The thiol group readily chemisorbs to metal surfaces, while the terminal carboxylic acid group provides a functional handle for subsequent chemical modifications.
Surface Functionalization
The carboxylic acid moiety on this compound can be reacted with amines or alcohols. This facilitates the introduction of diverse end-groups or the creation of multi-layered structures with tailored surface properties for advanced material design.
Materials Science and Nanotechnology
This molecule serves as a critical component in advanced materials research, particularly for controlling surface chemistry at the nanoscale. It is used in applications within micro/nanoelectronics and self-assembly material development.
| Molecular weight | 288.49 |
|---|---|
| Linear formula | HS(CH2)15CO2H |
| Assay | 99% |
| Storage temperature | 2-8°C |
| Application | Formation of interchain carboxylic anhydrides on self-assembled monolayers with Fluoro N,N,N′,N′-tetramethylforamidinium hexafluorophosphate.1 This compound is used in self-assembly to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized2 with various amines and alcohols to introduce more complex end groups or multiple layers.3 |
| Melting point | 65-69 °C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 16-Mercaptohexadecanoic acid used for?
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16-Mercaptohexadecanoic acid is used for forming self-assembled monolayers (SAMs), surface functionalization, and in materials science and micro/nanoelectronics applications. It enables the creation of hydrophilic surfaces and multi-layered structures.
What are the CAS number and formula for 16-Mercaptohexadecanoic acid?
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The CAS number for 16-Mercaptohexadecanoic acid is 69839-68-5, and its linear formula is HS(CH2)15CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 16-Mercaptohexadecanoic acid with an assay of 99%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
How should 16-Mercaptohexadecanoic acid be handled safely?
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16-Mercaptohexadecanoic acid carries the hazard statement H413, indicating it may cause long lasting harmful effects to aquatic life. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter. Store at 2-8°C.
How is 16-Mercaptohexadecanoic acid packed, shipped, and exported?
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As a global supplier and exporter of fine chemicals since 1998, Tech Serve Solutions ensures that 16-Mercaptohexadecanoic acid is carefully packed and exported in compliance with all relevant international shipping regulations.
How can I request a quote or sample of 16-Mercaptohexadecanoic acid?
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To request a quote or a sample of 16-Mercaptohexadecanoic acid, please contact our sales team through the website or via your usual communication channel, referencing the product name and CAS number.
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