16-Dehydroprogesterone
16-Dehydroprogesterone (CAS: 1096-38-4), a steroid with the molecular formula C21H28O2 and a molecular weight of 312.45 g/mol, is a key intermediate in organic synthesis. It serves as a valuable building block in the development of complex molecules and steroid derivatives. Its structure, featuring a pregnadiene dione core, makes it useful in areas such as asymmetric synthesis and biochemical research, contributing to advancements in chemical and biological sciences.
- IUPAC
- 4,16-Pregnadiene-3,20-dione

Chemical Synthesis Intermediate
16-Dehydroprogesterone functions as a crucial intermediate in the multi-step synthesis of various organic compounds. Its specific chemical structure allows for targeted modifications in the development of complex molecules and steroidal active pharmaceutical ingredients.
Asymmetric Synthesis
The compound's chiral nature makes it a valuable reagent in asymmetric synthesis. It enables chemists to construct stereochemically defined molecules, which is critical in the pharmaceutical industry for developing enantiomerically pure drugs.
Biochemical Research
As a bioactive small molecule, 16-Dehydroprogesterone is utilized in cell biology and biochemical studies. It can be employed to investigate steroid metabolism pathways and hormonal effects in biological systems.
| Molecular weight | 312.45 |
|---|---|
| Empirical formula | C21H28O2 |
| Assay | 97% |
| Melting point | 185-187 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP17A1(1586) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 16-Dehydroprogesterone used for?
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16-Dehydroprogesterone is used as a chemical intermediate in organic synthesis, particularly in asymmetric synthesis for creating complex molecules and steroid derivatives. It also finds application in biochemical research and cell biology studies.
What are the CAS and formula for 16-Dehydroprogesterone?
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The CAS number for 16-Dehydroprogesterone is 1096-38-4, and its molecular formula is C21H28O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 16-Dehydroprogesterone with a minimum assay of 97%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
How should 16-Dehydroprogesterone be handled safely?
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16-Dehydroprogesterone is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). It is also suspected of causing cancer (H351). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is 16-Dehydroprogesterone a controlled substance?
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The provided data does not indicate that 16-Dehydroprogesterone is a controlled substance.
How is 16-Dehydroprogesterone packaged and shipped?
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16-Dehydroprogesterone is carefully packaged to ensure stability and safety during transit. As a specialist global supplier, Tech Serve Solutions adheres to all regulations for exporting chemicals.
How can I request a quote or sample of 16-Dehydroprogesterone?
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To request a quote or sample of 16-Dehydroprogesterone, please contact our sales department through the website or by phone, providing your specific requirements.
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